Objective: To inform about the FDA's approval of a new starting regimen for lecanemab-irmb for Alzheimer's disease treatment. Approach: Method: T Method: h Meth
Objective: To evaluate the risk of ischemic optic neuropathy (ION) associated with the initiation of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) compa
Objective: To announce the joining of Dr. Michael Todinca, a neuromuscular neurologist, to Baptist Health Miami Neuroscience Institute. Approach: Clinical Focus
Objective: To analyze provisional mortality data for deaths occurring among US residents in 2025 and compare it with 2024 data. Approach: Data Analysis: Researc
Objective: To investigate whether menstrual fluid can reveal changes in endometrial epithelial signatures that may aid in the detection of endometriosis. Approa
Voice changes may indicate asthma or COPD exacerbations, with significant acoustic feature alterations observed before medication initiation.
In a study, 30 out of 38 exacerbations were detected by symptom questionnaires, highlighting limitations in current assessment methods.
Reproductive timing and breastfeeding duration were associated with laryngopharyngeal reflux, but total pregnancy count showed no significant differences.
An experimental metamaterial antenna improved ocular MRI signals, demonstrating potential for enhanced imaging but requiring further validation.
GLP-1 receptor agonists reduced lung fibrosis in diabetic mice post-COVID, with no significant changes in glucose levels observed.
Objective: To announce Amber Price's selection as a Fellow of the American Academy of Nursing. Approach: Recognition: Amber Price has been recognized for her ou
Objective: To evaluate the impact of pediatric emergency care capability on imaging patterns in pediatric patients treated in emergency departments, particularl
Objective: To provide specialized outpatient vascular care for patients undergoing dialysis and chemotherapy in the Hampton Roads region. Approach: Facility Ove
Objective: To investigate the association between routinely collected laboratory biomarkers and the risk of stress-related disorder diagnosis. Approach: Study D
Objective: To develop AI platforms that infer molecular information from pathology slides, making insights more accessible and faster for clinicians. Approach:
Objective: To determine if a genomic test can identify patients with hormone receptor-positive, HER2-negative early breast cancer who are most likely to benefit
Objective: To promote YUVEZZI, a prescription eye drop for treating presbyopia, through a national direct-to-consumer campaign, as reported by Business Wire. Ap
Objective: To announce the appointment of Mr. Christos Koutsidis as a Consultant Ophthalmologist and Ophthalmic Surgeon at The Retina Clinic London. Approach: A
Objective: To explore how precision medicine and bioanalytical approaches can enhance athletic performance and health monitoring. Approach: Case Study of Britto
Objective: To evaluate the efficacy of dual-site accelerated intermittent theta burst stimulation (aiTBS) targeting the left dorsolateral prefrontal cortex and
Dual-site accelerated intermittent theta burst stimulation may reduce suicidal ideation in adolescents with major depressive disorder compared to single-site stimulation.
The randomized clinical trial involved 59 patients aged 12 to 18 years, diagnosed with major depressive disorder and exhibiting significant suicidal ideation.
Mean Beck Scale for Suicide Ideation scores decreased more in the dual-site group, from 22.6 to 8.2, compared to the single-site group's decrease from 23.3 to 13.9.
Response rates for suicidal ideation were 59% in the dual-site group and 37% in the single-site group, with remission rates of 48% and 30%, respectively.
Common adverse events included pain at stimulation sites and dizziness, which resolved within approximately 30 minutes after treatment.
Objective: To explore the potential of in vivo CAR T-cell therapy for treating autoimmune diseases, addressing the limitations of current ex vivo approaches. Ap
Objective: To summarize recent advancements in CAR T cell therapy and gene therapy approaches targeting various cancers and conditions. Approach: CAR T Design T
CAR 422 is a mesothelin-targeting CAR T cell that shows activity in ovarian and pancreatic cancer by targeting a juxtamembrane stump of mesothelin.
Engineered regulatory T cells, or CAlleR Tregs, reduced allergic asthma symptoms in mice by suppressing allergen-specific immune responses.
A targeted radiopharmaceutical improved CAR T cell therapy in neuroblastoma models, enhancing tumor regression and reshaping the tumor microenvironment.
A liver-directed lentiviral gene therapy showed durable effects in mouse models of methylmalonic acidemia, with high gene transfer efficiency.
A gene therapy platform using engineered AAV5 capsids targets human glial cells in the brain, addressing challenges in neurological gene therapy.