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World Journal Of Urology

  • September 20, 2026
Diagnostic Testing for Urinary Tract Infections Using Molecular Methods: Uncertain Outcomes
  • Meghana Reddy
  • Christina Sze
  • Bonnie C. Prokesch
  • Philippe Zimmern
  • September 20, 2026
  1. Urinary tract infections (UTIs) are common bacterial infections that significantly impact women's health.
  2. Standard urine culture (SUC) is the gold standard for UTI diagnosis but has limitations in sensitivity and turnaround time.
  3. Molecular diagnostic methods, including PCR and NGS, offer faster results and broader pathogen detection compared to SUC.
  4. Despite the advantages of molecular diagnostics, their impact on clinical outcomes and antibiotic-guided cure rates remains uncertain.
  5. The systematic review included 12 studies published from 2023 to 2025, focusing on the efficacy of molecular diagnostics for UTIs.
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Int. Journal Of Computer Assisted Radiology And Surgery

  • September 19, 2026
Advancing the Utilization of Clinical Agent Data in a Virtual Environment: An Investigation into Data Structures and Constraints through a Pragmatic Digital Twin Approach
  • Sidra Rashid
  • Katarina Sliepkova
  • Lukas Bernhard
  • Sonja Stabenow
  • Emily Spicker
  • Stefanie Rinderle-Ma
  • Johannes Fottner
  • Dirk Wilhelm
  • Maximilian Berlet
  • September 19, 2026
  1. The increasing availability of digital healthcare data has accelerated the adoption of AI for disease identification and predictive analytics.
  2. Healthcare data are often heterogeneous and unstructured, leading to significant interoperability challenges among various Electronic Health Record systems.
  3. Patient-data fragmentation hinders the integration of multi-modal datasets necessary for effective data mining and machine learning in healthcare.
  4. OMNI-SYS is a pragmatic digital twin framework designed to model hospital agents as objects, facilitating real-time updates and context-rich data extraction.
  5. A feasibility study at TUM University Hospital assessed the application of oHIS-like platforms in recording pre-operative patient tracks using volunteer participants.
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Bmj Paediatrics Open

  • September 19, 2026
Health Effects of Climate Change on Canadian Children: A Comprehensive Systematic Review
  • Daniel Helldén
  • Kirsten Sjonnesen
  • Luis D Virla
  • Sherilee L Harper
  • Francois Bernier
  • Steven Bryant
  • Benedikt Hallgrímsson
  • September 19, 2026
  1. Canada is warming at approximately twice the global average, leading to significant health risks for children.
  2. The systematic review identified 71 studies linking climate change to child health impacts, focusing on extreme temperatures and wildfires.
  3. Children's health vulnerabilities are exacerbated by existing inequities, particularly among First Nations, Inuit, and Métis communities.
  4. Quality assessment of studies revealed concerns regarding representativeness and bias, highlighting the need for more robust research.
  5. The findings emphasize the urgency for tailored interventions addressing climate change impacts on child health in Canada.
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European Radiology

  • September 19, 2026
Assessment of Coronary Stents in Vivo Through Photon-Counting Computed Tomography: A Study of Diagnostic Efficacy
  • Pietro G. Lacaita
  • Valentin Bilgeri
  • Philipp Spitaler
  • Benedikt Kindl
  • Wolfgang Dichtl
  • Ivan Lechner
  • Sebastian Reinstadler
  • Guy Friedrich
  • Gerlig Widmann
  • Gudrun M. Feuchtner
  • September 19, 2026
  1. Coronary CTA is recommended as the first-line diagnostic strategy for suspected chronic coronary syndromes by ESC and ACC/AHA guidelines.
  2. Conventional EID CT faces challenges in assessing coronary stents due to blooming artifacts and partial volume effects.
  3. PCCT offers improved spatial resolution and lower electronic noise, enhancing image quality for coronary stent assessment.
  4. The study aims to evaluate the in vivo diagnostic performance of ultrahigh-resolution PCCT compared to EID CT.
  5. Eligibility for the study was restricted to patients with previous stent implantation undergoing coronary CTA.
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Bmj Paediatrics Open

  • September 19, 2026
Association Between Prenatal Urinary BTEX Metabolite Concentrations and Gestational Duration: Initial Findings from a Birth Cohort in Metropolitan Detroit
  • Homègnon A Ferréol Bah
  • Qiong Zhang
  • Yichu Wang
  • Emily Leydet
  • Mei Lu
  • Judy Westrick
  • Paul Stemmer
  • Christine Cole Johnson
  • Jennifer K Straughen
  • Andrea E Cassidy-Bushrow
  • September 19, 2026
  1. This study measured urinary BTEX metabolites in 40 pregnant participants to explore their relationship with gestational length.
  2. Negative correlations were found between ethylbenzene metabolite phenylglyoxylic acid and gestational length (ρ=−0.37, p=0.018).
  3. Xylene metabolite methylhippuric acid also showed a negative correlation with gestational length (ρ=−0.35, p=0.026).
  4. Increased exposure to BTEX metabolites was associated with shorter gestational length, particularly among stratified infant sex groups.
  5. The study highlights the need for further research with a larger cohort to confirm associations between BTEX metabolites and preterm birth.
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Bmj Paediatrics Open

  • September 19, 2026
Assessing the Effects of the COVID-19 Pandemic on Child Protection Service Referrals at a Tertiary Care Facility in Vienna, Austria
  • Chryssa Grylli
  • Sophie Klomfar
  • Johanna Brandlechner
  • Laura Schaller
  • Katharina Weimann
  • Anastasia Pantazidou
  • Eva Mora-Theuer
  • Christoph Krall
  • Catherine Quantin
  • Susanne Greber-Platzer
  • September 19, 2026
  1. The study analyzed 401 suspected child maltreatment cases referred to FOKUS in Vienna from March 2019 to March 2023.
  2. During the pandemic, referrals for suspected physical abuse decreased by 55.3%, while suspected sexual abuse cases remained stable.
  3. Post-pandemic, suspected physical abuse reports returned to pre-pandemic levels, but suspected sexual abuse cases increased significantly.
  4. The median age of patients in suspected sexual abuse cases progressively increased over time, indicating changing victim profiles.
  5. Psychological support needs rose during the pandemic and remained elevated afterward, highlighting ongoing mental health challenges.
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Bmj Paediatrics Open

  • September 19, 2026
Validation of Neurodevelopmental Evaluation Tools for Early Identification of High-Risk Infants in Zimbabwe: A Protocol for the Child Development Observation Study (ChiDO)
  • Louisa Mudawarima
  • Nicole Santos
  • Gwendoline L Chimhini
  • Hilda A Mujuru
  • Rosemary Magonya
  • Rakesh Ghosh
  • Susanne P Martin-Herz
  • September 19, 2026

Get a concise, at-a-glance scorecard that distills clinical guidelines into key recommendations, patient insights, and treatment considerations.

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Dermatology And Therapy

  • September 19, 2026
Exploring the Microbiome's Influence on Lichen Sclerosus: Insights into Pathophysiology and Treatment Options
  • Marta Kasprowicz-Furmańczyk
  • Witold Chmielnicki
  • Natalia Zdanowska
  • Agnieszka Owczarczyk-Saczonek
  • September 19, 2026
  1. Lichen sclerosus (LS) is a chronic inflammatory and fibrotic dermatosis, traditionally classified as an autoimmune condition.
  2. Microbiome dysbiosis may contribute to LS pathogenesis and is associated with an increased risk of squamous cell carcinoma.
  3. Studies show heterogeneous microbiome alterations in LS across various anatomical sites, influenced by methodological variability.
  4. Dysbiosis may drive immune dysregulation and chronic inflammation, potentially through mechanisms involving mucosa-associated invariant T cells.
  5. Further longitudinal and interventional research is needed to establish causality and clinical applicability of microbiome findings in LS.
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Acta Paediatrica

  • September 19, 2026
Prevalence and Contributing Factors of Late-Onset Hypoglycemia in Infants with Extremely Low Gestational Age or Birth Weight
  • Lara Canova
  • Roland P. Neumann
  • Sven M. Schulzke
  • September 19, 2026
  1. Late-onset hypoglycemia occurs in clinically stable preterm infants after the first week of life, often without clinical signs.
  2. The study focused on infants born extremely preterm or at extremely low birth weight to assess late-onset hypoglycemia incidence.
  3. Late-onset hypoglycemia was defined as a blood glucose concentration < 2.6 mmol/L at a postnatal age of ≥ 8 days.
  4. The investigation aimed to identify demographic, clinical, and nutritional risk factors associated with late-onset hypoglycemia.
  5. Neurodevelopmental outcomes related to late-onset hypoglycemia in this high-risk population remain uncertain and were assessed.
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Drugs - Real World Outcomes

  • September 19, 2026
Analysis of Early Stage Melanoma Management and Treatment Approaches: Findings from a Multicenter Chart Review
  • Collin M. Costello
  • Maria L. Wei
  • James Isaacs
  • Elizabeth M. Gaughan
  • Adina Greene
  • Alexandra So
  • Xiaochen Zhong
  • Jara Majuelos-Melguizo
  • Kavita Gandhi
  • Claudia Rey
  • Alicia Delibes
  • Rosemarie Barnett
  • Mizuho Fukunaga-Kalabis
  • Nawab Qizilbash
  • Irene M. Shui
  • Xiang-Lin Tan
  • September 19, 2026
  1. Early-stage cutaneous melanoma (IB–IIC) is primarily managed through surgery, often with sentinel lymph node biopsy, per NCCN guidelines.
  2. As melanoma stage increases, systemic drug therapy and radiotherapy usage rise, with systemic therapy being predominant in second-line treatments.
  3. Higher-stage melanoma is linked to receiving more treatment lines, indicating a need for novel therapies and optimized treatment sequencing.
  4. The study aimed to characterize real-world treatment patterns for early-stage melanoma, highlighting gaps in current research and practice.
  5. The investigation involved four US institutions and focused on patients aged ≥ 18 years with newly diagnosed stage IB–IIC melanoma.
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Bmj Paediatrics Open

  • September 19, 2026
Prevalence of Anaemia in Indian Adolescent Girls: Analyzing Socioeconomic Disparities and Influencing Factors Using National Survey Data
  • Pritam Halder
  • Kathirvel Srinath
  • Anamika Das
  • Sushanta Sarkar
  • Indra Shekhar Prasad
  • Ravneet Kaur
  • Shivani Rathor
  • Esha Das
  • Anshul Mamgai
  • Manish Chandra Prabhakar
  • Chandramohan Kumar
  • Arnab Ghorui
  • September 19, 2026
  1. Anaemia prevalence among Indian adolescent girls aged 15-19 years is 59.1%, with 60.2% in rural areas and 56.6% in urban areas.
  2. Wealth index is the largest contributor to the urban-rural anaemia disparity, accounting for 52.4% of the difference.
  3. Other significant factors influencing anaemia include region (21.7%), caste (17.3%), healthcare access (12.6%), and fruit intake (8.2%).
  4. The study utilized data from the National Family Health Survey-5, involving 113,606 adolescent girls and measuring haemoglobin levels.
  5. Comprehensive interventions are needed to address anaemia and associated disparities among Indian adolescent girls, focusing on diet and socioeconomic factors.
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Int. Journal Of Computer Assisted Radiology And Surgery

  • September 19, 2026
A Transformer-Based U-Net Model for Magnetic Resonance Elastography
  • Weiheng Zhong
  • Matthew W. Urban
  • Hadi Meidani
  • September 19, 2026
  1. Magnetic resonance elastography (MRE) quantifies tissue mechanical properties using displacement fields and specialized inversion algorithms.
  2. Traditional inversion methods like Direct Inversion (DI) and Local Frequency Estimation (LFE) face challenges with heterogeneous organs and experimental noise.
  3. Machine learning techniques, including physics-informed neural networks and neural operators, aim to improve MRE inversion speed and accuracy.
  4. Challenges in MRE include the lack of large-scale datasets for training and limited exploration of model architectures for clinical application.
  5. The proposed U-Net Transformer Neural Operator framework combines local detail with global context and uses physics-informed fine-tuning for patient-specific data.
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Drug Safety

  • September 19, 2026
An Algorithm for Text Mining to Detect Potential Drug Pair Interactions in Prescribing Cascades: Development and Internal Validation Using the Prescribing Inappropriateness Assessment (PINA) Tool
  • Massimo Carollo
  • Anna Forti
  • Salvatore Crisafulli
  • Luca L’Abbate
  • Irene Cristini
  • Federica Soardo
  • Marilisa Giustina Stano
  • David Bellantuono
  • Davide Benetti
  • Riccardo Lora
  • Gianluca Trifirò
  • September 19, 2026
  1. An algorithm was developed to identify drug pairs potentially representing prescribing cascades during medication review.
  2. Internal validation indicated the algorithm produced few spurious matches, enhancing detection of drug pairs supported by literature.
  3. The tool prioritizes candidate drug pairs for clinical assessment but does not confirm prescribing cascades or initiate deprescribing.
  4. PINA software is designed to assist healthcare professionals with structured medication reviews in patients exposed to polypharmacy.
  5. The algorithm analyzes adverse drug reactions and therapeutic indications to report candidate drug pairs potentially compatible with prescribing cascades.
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World Journal Of Urology

  • September 19, 2026
Does Preoperative Active Surveillance Elevate the Risk of Negative Pathological Outcomes or Subsequent Treatment for Prostate Cancer Following Radical Prostatectomy?
  • Ingrid Hannestad
  • Tor Åge Myklebust
  • Sophie D. Fosså
  • Stig Muller
  • Kirsti Aas
  • September 19, 2026
  1. Men with low- and favorable intermediate-risk prostate cancer often undergo active surveillance to avoid overtreatment.
  2. Deferred radical prostatectomy after active surveillance may be associated with more adverse pathological findings compared to immediate surgery.
  3. A Swedish study indicated that delayed radical prostatectomy increases the risk of salvage radiotherapy, but newer data showed no increase in post-surgery treatment.
  4. The study utilized data from the Norwegian Prostate Cancer Registry, including men diagnosed between 2009 and 2022.
  5. At diagnosis, men undergoing deferred radical prostatectomy had more favorable disease characteristics than those receiving immediate surgery.
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MDSpire News

  • September 18, 2026
Retained silk may underlie late postvasectomy fistula
  • Andrea Surnit
  • September 18, 2026
  • 4 min

Objective: To investigate a case of vasocutaneous fistula occurring 3 years after vasectomy, potentially related to retained silk ligature and chronic inflammat

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2 min

MDSpire News

  • September 18, 2026
Nirsevimab may curb RSV severity
  • Andrea Surnit
  • September 18, 2026
  • 3 min

Objective: To assess the effectiveness of nirsevimab against respiratory syncytial virus (RSV) disease requiring hospital-based care among infants during the fi

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Inside Dental Hygiene

  • September 18, 2026
Experts Call for Risk-Based Periodontal Prevention
  • News Staff
  • September 18, 2026
  • 4 min

Objective: To develop recommendations for individualized, risk-based approaches to preventing and managing periodontal diseases, including the selective use of

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Inside Dentistry

  • September 18, 2026
Ultradent Adds VALO XS and VALO XG Curing Lights
  • News Staff
  • September 18, 2026
  • 2 min
  1. Ultradent has launched the VALO XS and VALO XG curing lights, expanding its VALO X curing light family.
  2. The VALO XG features an 11.7-mm lens and offers Standard Power and Xtra Power curing modes.
  3. The VALO XS is designed for pediatric and orthodontic applications with a 9.7-mm lens and includes Ortho Quadrant mode.
  4. Both curing lights have an aerospace-grade aluminum construction and can operate corded or cordless.
  5. Ultradent provides a five-year manufacturer's warranty for both the VALO XS and VALO XG curing lights.
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