Objective: To update the sotatercept-csrk (Winrevair) label based on efficacy and safety data from the phase 3 HYPERION trial in adults with pulmonary arterial
Oral-B and Crest launched limited-edition oral care products featuring seven NFL teams as part of their partnership with the league.
The collection includes Oral-B iO Series 2 electric toothbrushes, manual toothbrushes, Crest 3DWhite Toothpaste, and mouthwash.
Products are available at select retailers nationwide and feature team-inspired designs for the Eagles, Cowboys, Chiefs, 49ers, Buccaneers, Falcons, and Panthers.
NFL players and fans, including Dallas Goedert and Haley Cavinder, are promoting the collection during the 2026 season.
Oral-B and Crest are the official oral care partners of the NFL, providing toothbrushes, toothpaste, floss, and mouthwash.
Objective: To introduce the KATANA™ Zirconia ONE SPEED's new sintering capability using the CEREC® SpeedFire furnace. Approach: Sintering Process: KATANA Zircon
Objective: To evaluate a microneedle patch for measuring the kidney injury biomarker neutrophil gelatinase-associated lipocalin in dermal interstitial fluid. Ap
A microneedle patch effectively measures neutrophil gelatinase-associated lipocalin in dermal interstitial fluid, indicating kidney injury.
The patch remains functional after exposure to high temperatures, retaining 94% of its fluorescence signal after temperature cycling.
Neutrophil gelatinase-associated lipocalin levels increased within four hours in mice with acute kidney injury, preceding changes in serum creatinine.
The study demonstrated strong correlation between interstitial fluid and plasma measurements, although concentrations were lower in interstitial fluid.
Further research is required to establish interstitial fluid thresholds, assess diagnostic performance, and explore multiplexed kidney biomarker measurements.
Scleral tattooing, or eyeball tattooing, involves injecting ink under the bulbar conjunctiva and is a practice that began in 2007.
The couple in the article underwent refractive lens exchange surgery after having their sclerae tattooed, documenting their medical history extensively.
Complications from scleral tattooing can include severe visual outcomes, with 71% of reported cases experiencing globe penetration.
Despite potential risks, the couple's surgery was uneventful, with no impact from the tattoo on their surgical outcomes or ocular assessments.
The artist responsible for their tattoos emphasized that proper technique ensures the pigment does not obstruct inner eye structures.
Objective: To highlight the case of a young athlete experiencing an acute aortic dissection and the medical response that followed. Approach: Patient Background
Objective: To analyze the impact of 988 telecom fees on state funding for suicide prevention and crisis services from fiscal years 2021 to 2026. Approach: Study
CCRM established DeepTech Bio Lab to explore digital tools and advanced technologies for cell and gene therapy industrialization.
Access to capital is the primary bottleneck in cell and gene therapy, requiring demonstration of durable commercial success to attract investors.
Progress in reprogramming induced pluripotent stem cells for safe and effective therapies is significant but underappreciated.
The belief that cell and gene therapy development is entirely different from past experiences is challenged by historical parallels in treatment approaches.
Future drug development will increasingly rely on data, AI, and quantum platforms, transforming the industry towards 'techbio' alongside 'biotech'.
A 40-year-old man with IgG4-related ophthalmic disease experienced severe hypersensitivity reactions to rituximab after partial response to glucocorticoids and mycophenolate mofetil.
Obinutuzumab was administered after rituximab was discontinued, resulting in no infusion reactions and significant clinical improvement within one month.
Serum IgG4 levels decreased from 861 mg/dL to 49.1 mg/dL, and repeat imaging showed substantial reduction in lacrimal-gland enlargement after obinutuzumab treatment.
Obinutuzumab may offer a viable treatment alternative for patients intolerant to rituximab in IgG4-related disease, although its use is currently off-label.
The case highlights the potential of obinutuzumab in managing IgG4-related orbital involvement, but further studies are needed to confirm its efficacy and safety.
Objective: To evaluate the safety and feasibility of conducting laparoscopic sleeve gastrectomy (LSG) concurrently with left ventricular assist device (LVAD) im
Objective: To assess hourly patterns of insulin delivery and glucose profiles in children using an automated insulin delivery system. Approach: Statistical Anal
Objective: To characterize surgical re-interventions in non-Fuchs corneal dystrophies and identify surgical techniques linked to further interventions. Approach
Corneal dystrophies are inherited disorders that affect corneal transparency and visual function, with Fuchs endothelial corneal dystrophy being the most common subtype.
Surgical options for non-Fuchs corneal dystrophies include superficial ablation and full-thickness surgery, with recurrence posing a significant challenge.
This study analyzed 372 non-Fuchs corneal dystrophy specimens over eight decades, focusing on surgical re-interventions and their associated procedures.
The research aimed to quantify the proportion of re-interventions for each dystrophy type and evaluate the surgical techniques linked to these cases.
The study adhered to ethical standards and utilized the IC3D classification system to categorize corneal dystrophies based on their features.