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Conexiant

July 22, 2026

FDA Expands Pediatric Allergy Nasal Spray Use

Kathryn Wighton
July 22, 2026
2 min

Takeaways
Poll

The FDA has expanded the indication for RYALTRIS nasal spray to include children aged 6 to under 12 years with seasonal allergic rhinitis.
The approval was based on a phase 3 trial with 446 pediatric patients showing greater improvement in nasal symptoms compared to placebo.
RYALTRIS is a fixed-dose combination nasal spray containing olopatadine hydrochloride and mometasone furoate.
The product was initially approved in 2022 for adults and children aged 12 years and older.
Common adverse reactions include dysgeusia, epistaxis, and nasal discomfort, with warnings for various serious conditions.

...more

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Conexiant

July 22, 2026

BiZact May Improve Adult Tonsillectomy Recovery

Andrea Surnit
July 22, 2026
3 min

Poll

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Conexiant

July 22, 2026

Trump’s Personnel Agency Says It Will Remove Some Identifying Info as It Sweeps Up Medical Records

Amanda Seitz
Maia Rosenfeld
Darius Tahir
July 22, 2026
7 min

Takeaways
Poll

The Trump administration plans to collect medical records of over 8 million federal workers, retirees, and their families.
The Office of Personnel Management will pseudonymize personal health information before analysis, but retains the right to reidentify records.
Sixty-five insurance companies will provide detailed health data to OPM to help identify fraud in federal health benefit programs.
Concerns about privacy persist, with critics arguing that pseudonymization may not sufficiently protect sensitive information.
OPM's plan includes analyzing records from Medicare for dual enrollees to enhance fraud detection efforts.

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The Ophthalmologist

July 22, 2026

Looking Deeper With STOC-T

July 22, 2026
3 min

Takeaways

Spatio-temporal optical coherence tomography (STOC-T) improves imaging depth and contrast by changing light delivery and detection methods.
STOC-T preserves ballistic photons while suppressing multiply scattered light, enhancing the quality of structural information.
The technique enables high-resolution imaging of ocular structures, including the retina-choroid complex and corneal layers.
STOC-T has applications in functional retinal imaging, capturing rapid retinal dynamics linked to photoreceptor physiology.
Challenges for clinical adoption of STOC-T include large data sets, high-speed camera requirements, and computational processing needs.

...more

The Ophthalmologist

July 22, 2026

Alcohol Use Associated with Advanced Presbyopia

July 22, 2026
3 min

Takeaways

A Japanese study found that regular alcohol consumption may accelerate presbyopia progression in men.
The study evaluated 6,258 adults aged 40–79 years for lifestyle factors affecting presbyopia severity.
Logistic regression identified male sex and alcohol consumption as significant risk factors for advanced presbyopia.
Male drinkers had higher near add power requirements than non-drinkers, particularly evident in ages 50–59.
The study suggests chronic alcohol exposure may impair ciliary muscle function and contribute to earlier lens sclerosis.

...more

The Ophthalmologist

July 22, 2026

Largest Ever UK Survey of People with Glaucoma

July 22, 2026
3 min

Poll

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The Analytical Scientist

July 22, 2026

The Proteomics of Precision – with Jennifer Van Eyk: Part 2

James Strachan
July 22, 2026
10 min

Poll

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The Analytical Scientist

July 22, 2026

Mass Spec Roundup: Oocytes, Ligands, Ion Traps, and Corals

Henry Thomas
July 22, 2026
7 min

Takeaways

The seGRAP workflow enables single-oocyte N-glycome profiling on routine mass spectrometry platforms with minimal sample loss.
Single-oocyte analysis identified 46 N-glycan compositions, revealing a conserved glycan repertoire across donors and maturation stages.
Dynamic combinatorial libraries and activity-based protein profiling enhance covalent ligand discovery throughput by 10- to 20-fold.
A software-defined retrofit restored mass analysis and multistage fragmentation to a legacy linear ion trap for training purposes.
The retrofit demonstrated multistage tandem mass spectrometry capabilities, isolating and activating ions without changing trapping voltage.

...more

The Pathologist

July 22, 2026

Why Pathology Needs Enterprise Imaging

Jessica Allerton
July 22, 2026
5 min

Summary
Poll

Objective: To highlight the importance of enterprise imaging in pathology and the role of the Society for Imaging Informatics in Medicine (SIIM) in supporting t

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The Pathologist

July 22, 2026

The Eye May Hold Clues to Long COVID

July 22, 2026
3 min

Poll

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Conexiant

July 21, 2026

ICIs May Support Nonsurgical dMMR Cancer Care

Andrea Surnit
July 21, 2026
3 min

Poll

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Conexiant

July 21, 2026

Four Patterns in End-of-Life Decline?

Andrea Surnit
July 21, 2026
4 min

Summary
Takeaways
Insight Report
Quiz
Poll
Clinical Scorecard

Objective: To analyze the trajectories of physical, cognitive, and psychological functioning during the final decade of life and identify patterns of decline am

...more

Patients experienced significant declines in physical, cognitive, and psychological functioning during the final decade of life.
The study analyzed data from 79,305 adults aged 45 and older across 17 countries, with 12,135 participants dying during follow-up.
Four distinct patterns of decline were identified among decedents, with nearly 44% maintaining relatively high functioning.
Higher socioeconomic status was linked to a lower likelihood of experiencing rapid decline across multiple functional domains.
The findings suggest that early screening for functional impairment may help address health inequalities at the end of life.

...more

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The Pathologist

July 21, 2026

Life Has No Uncrossable Hurdles

Gang He
July 21, 2026
7 min

Summary
Takeaways
Quiz
Clinical Scorecard

Objective: To share a personal narrative of overcoming professional challenges and a significant misdiagnosis incident in pathology. Approach: Personal Experien

...more

2 min

The author faced a misdiagnosis ruling that damaged their reputation as a pathologist, despite a low error rate in their case reports.
A renowned Canadian pathologist concluded that the author's error rate was well below the threshold for retraining set by the College of American Pathologists.
The author experienced significant personal and professional challenges, including isolation and exploitation, after the misdiagnosis was publicized.
Despite setbacks, the author successfully mentored 88 Chinese medical students, with over 75% entering US residency programs.
The author found recovery and confidence through support from family, friends, and a passion for tennis, achieving notable success in competitions.

...more

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The Pathologist

July 21, 2026

Pathology Blueprint Backs In Vitro Diagnostics

July 21, 2026
3 min

Summary
Quiz
Clinical Scorecard

Objective: To advocate for the wider adoption of in vitro diagnostics (IVDs) to support the UK NHS's 10-Year Health Plan, as stated in the report by the Royal C

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1 min

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The Medicine Maker

July 21, 2026

The Power List 2026 is Live

July 21, 2026
1 min

Summary
Takeaways
Insight Report
Poll
Clinical Scorecard

Objective: To celebrate individuals contributing to advancements in drug discovery. Approach: Advancements in Drug Discovery: New drug discovery technologies an

...more

New drug discovery technologies are advancing therapies across various modalities, including molecular glues and protein degraders.
Cell therapies are expanding their applications to solid tumors and autoimmune diseases, showcasing significant potential.
Challenges remain in demonstrating value to investors in a capital-constrained environment within the industry.
The coexistence of different therapeutic modalities as part of a mixed ecosystem is a critical consideration for the field.
The Power List 2026 features 60 individuals recognized for their contributions, with 20 in each category: Small Molecules, Biopharma, and Advanced Medicines.

...more

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The Ophthalmologist

July 21, 2026

Pupil Test Flags Recovery Potential

July 21, 2026
2 min

Summary
Takeaways
Insight Report
Poll

Objective: To evaluate the predictive value of the late light-off response of the pupil in assessing recovery of consciousness in patients with severe brain inj

...more

A 13-second bedside eye test may predict recovery of consciousness in patients with severe brain injuries.
The late light-off response of the pupil predicted improvements in consciousness seven days later.
Standard pupil measurements like the Neurological Pupil Index did not predict later recovery.
The study involved 250 patients with impaired consciousness and 30 healthy controls.
The late light-off response may indicate recovery potential not visible during routine assessments.

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The Ophthalmologist

July 21, 2026

Amniotic Dressing Shows NHS Promise

July 21, 2026
3 min

Summary
Insight Report
Quiz

Objective: To evaluate the effectiveness of a sutureless amniotic membrane dressing in treating persistent corneal epithelial defects (PEDs) in patients. Approa

...more

2 min

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The Ophthalmologist

July 21, 2026

Endogenous Endophthalmitis and Missed Diagnoses

July 21, 2026
3 min

Summary
Quiz
Clinical Scorecard

Objective: To highlight the diagnostic challenges and clinical presentation of endogenous endophthalmitis. Approach: Study Design: Retrospective review of 50 ey

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2 min

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