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MDSpire News

  • October 20, 2026
FDA issues Class I recall for Philips ultrasound
  • Teraya Smith
  • October 20, 2026
  • 2 min
  1. The FDA classified a correction involving Philips Lumify diagnostic ultrasound systems as a Class I recall on October 19.
  2. As of September 29, 2026, the FDA had received reports of 8 serious injuries and 4 deaths associated with Lumify functionality issues.
  3. A software issue may unexpectedly require transducer re-registration, which needs Wi-Fi or cellular connectivity and can prevent scanning until completed.
  4. Unstable or disconnected USB connections may interrupt imaging, while connectivity-related failures pose particular risks in prehospital settings.
  5. Philips advised using Lumify only where network access is readily available unless a backup ultrasound device is immediately available, and is developing a software update.
...more

Baptist Health South Florida

  • October 20, 2026
Sarah Talebagha, M.D., Joins Baptist Health Heart & Vascular Care
  • October 20, 2026
  • 4 min

Objective: Announce vascular surgeon Sarah Talebagha’s appointment at Baptist Health Miami Cardiac & Vascular Institute and summarize her training, clinical int

...more
2 min

MDSpire News

  • October 20, 2026
Annual dementia cases may double by 2050
  • Andrea Surnit
  • October 20, 2026
  • 4 min

Objective: Estimate dementia incidence across populations and project annual new cases worldwide through 2050. Approach: Study design: Harmonized meta-analysis

...more
2 min

The Medicine Maker

  • October 20, 2026
How Genomics Is Personalizing Drug Discovery
  • Mouj Hijazi
  • October 20, 2026
  • 8 min

Objective: The article examines the objective, findings, and clinical context described in How Genomics Is Personalizing Drug Discovery. Approach: Population-sc

...more
3 min

MDSpire News

  • October 20, 2026
Nearly half with HIV may be 65+ by 2040
  • Andrea Surnit
  • October 20, 2026
  • 4 min
  1. A model projected that adults aged 65 years or older would make up 46% of people with diagnosed HIV in 24 US states by 2040, up from 23% in 2025.
  2. The projected number of people aged 65 years or older with diagnosed HIV would increase from approximately 214,000 in 2025 to 459,000 in 2040.
  3. The median age of people with diagnosed HIV was projected to rise from 51 years in 2025 to 61 years in 2040, while the general adult population median would remain near 44 years.
  4. Aging projections varied substantially by state, with median age reaching 67 years in California and New York but falling to 39 years in Arkansas and Oklahoma.
  5. The projections assumed recent HIV transmission and public health trends would continue, and changes in transmission or survival could alter the findings.
...more

The Medicine Maker

  • October 20, 2026
Musings from The Power List: Piers Ingram
  • Piers Ingram
  • October 20, 2026
  • 5 min

Objective: The article examines the objective, findings, and clinical context described in Musings from The Power List: Piers Ingram. Approach: Professional hig

...more
2 min

The Pathologist

  • October 20, 2026
Peptide Biomarkers in Clinical Diagnostics
  • Compound Vitality Research Team
  • October 20, 2026
  • 6 min
  1. Peptide patterns can reflect protein processing, protease activity, and tissue response, potentially adding biological specificity beyond measurements of protein abundance.
  2. Mass spectrometry enables broad peptide profiling without requiring a separate antibody for each candidate, making it useful for biomarker discovery.
  3. Peptide measurements are sensitive to specimen handling and analysis, so collection, storage, preparation, and reagent characterization require careful control.
  4. MALDI-TOF studies reported informative serum peptide features and strong model discrimination for hepato-pancreato-biliary cancers, but these findings require further validation.
  5. Clinical adoption requires reliable performance in independent cohorts and laboratories, with pathologists helping define intended use, comparison groups, and specimen context.
...more

The Pathologist

  • October 20, 2026
PathVisions 2026: Mapping Cancer’s Cellular Ecosystem
  • October 20, 2026
  • 3 min
  1. MIFSpace is an open-source computational framework for integrating multiplex immunofluorescence images from adjacent tissue sections.
  2. The framework expands the effective marker space for high-dimensional cellular phenotyping and spatial biology.
  3. MIFSpace uses quantitative cross-panel concordance analysis to assess marker consistency across nonidentical tissue sections.
  4. The researchers aim to use MIFSpace to study tumor immune neighborhoods, immune exclusion, and multicellular ecosystems related to immunotherapy response and resistance.
  5. The researchers envision MIFSpace supporting biomarker discovery and precision oncology by integrating cellular identities, spatial relationships, and molecular measurements.
...more

The Analytical Scientist

  • October 20, 2026
What Will Analytical Science Look Like in 2036? Part Two: Beyond AI
  • October 20, 2026
  • 11 min

Get quick, clinically relevant Q&A that turns long-form articles into clear answers for faster learning and discovery.

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The Analytical Scientist

  • October 20, 2026
PFAS Linked to Lipid Changes in Children
  • October 20, 2026
  • 3 min

Objective: To examine associations between PFAS exposure and metabolic markers in children, including whether associations differed by sex and pubertal stage. A

...more
2 min

The Pathologist

  • October 20, 2026
Special Series: Advances in Molecular Pathology
  • October 20, 2026
  • 1 min

Objective: Present recent developments and perspectives in precision diagnostics and molecular pathology. Approach: Collection: The Pathologist brings together

...more
1 min

The Medicine Maker

  • October 20, 2026
How Genomics Is Personalizing Drug Discovery
  • Mouj Hijazi
  • October 20, 2026
  • 8 min

Objective: The article examines the objective, findings, and clinical context described in How Genomics Is Personalizing Drug Discovery. Approach: Population-sc

...more
3 min

The Medicine Maker

  • October 20, 2026
Gene Therapy Approach Shows Promise for Hydrocephalus
  • October 20, 2026
  • 3 min
  1. Researchers developed an AAV5-CMV-DTR platform to target choroid plexus epithelial cells and reduce cerebrospinal fluid production in mice.
  2. In adult mice with kaolin-induced hydrocephalus, treatment within 6 to 10 hours reduced brain edema and corpus callosum MRI abnormalities.
  3. Treatment did not substantially reduce ventricular enlargement or cause ventricular collapse in the adult mouse model.
  4. In neonatal mice, choroid plexus ablation reduced neuroblast populations in the subventricular and hippocampal subgranular zones.
  5. Neonatal treatment was associated with smaller hippocampal and overall brain volumes and modestly reduced exploratory locomotor activity.
...more

American Association For Respiratory Care

  • October 20, 2026
Chronic Respiratory Conditions in the United States: Trends and Future Projections
  • Debbie Bunch
  • October 20, 2026

Objective: To assess U.S. prevalence and mortality trends for five chronic respiratory conditions from 1990 to 2023 and project their trajectories through 2050.

...more
3 min

Surgical Endoscopy

  • October 20, 2026
Correction: VFA/TAMAI predicts worsening organ damage following central catheter removal for catheter-related bloodstream infection in patients with enterocutaneous fistula
  • Zhan Yu
  • Lei Luo
  • Risheng Zhao
  • Yunzhao Zhao
  • Zheng Yao
  • Xin Xu
  • October 20, 2026

Objective: The article examines the objective, findings, and clinical context described in Correction: VFA/TAMAI predicts worsening organ damage following centr

...more
1 min

Journal Of Medical Internet Research

  • October 20, 2026
Smart Wearables and AI May Detect Early Signs of Postpartum Psychosis
  • Benedette Cuffari
  • October 20, 2026

Objective: The article examines why early signs of postpartum psychosis (PPP) can be difficult to detect and whether wearable sensors could help identify change

...more
3 min

World Journal Of Urology

  • October 20, 2026
Survival Outcomes After Lutetium-177-PSMA-617 for Metastatic Castration-Resistant Prostate Cancer by Baseline Tumor Features
  • Mike Wenzel
  • Quynh Chi Le
  • Carolin Siech
  • Benedikt Hoeh
  • Konrad Klimek
  • Christian Happel
  • Fred Saad
  • Felix Preisser
  • Derya Tilki
  • Markus Graefen
  • Thomas Steuber
  • Tobias Maurer
  • Maximilian C. Kriegmair
  • Pierre I. Karakiewicz
  • Felix K. H. Chun
  • Daniel Groener
  • Philipp Mandel
  • October 20, 2026

Objective: To assess progression-free survival (PFS) and overall survival (OS) after Lu-177-PSMA treatment according to baseline metastatic timing, Gleason scor

...more
3 min

Hernia

  • October 20, 2026
Correction: Technical refinements to pediatric laparoscopic percutaneous extraperitoneal closure for adult indirect inguinal hernia
  • Shoko Kato
  • Takuya Saito
  • Kenitiro Kaneko
  • Remi Kondo
  • Nozomi Matsushita
  • Yasuyuki Fukami
  • Tsuyoshi Sano
  • October 20, 2026

Objective: To correct two errors in the original article. Approach: Patients section: “Approval number: blinded” was corrected to “approval number: 2022-165”. F

...more
1 min