MDSpire - MDSpire Home
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

MDSpire News

  • November 6, 2026
FDA approves amivantamab for head and neck cancer
  • Mouj Hijazi
  • November 6, 2026
  • 3 min

Objective: The article examines the objective, findings, and clinical context described in FDA approves amivantamab for head and neck cancer. Approach: Treatmen

...more
2 min

MDSpire News

  • November 6, 2026
Can red tattoos harbor keratoacanthoma?
  • Andrea Surnit
  • November 6, 2026
  • 2 min

Objective: To describe a keratoacanthoma arising within red tattoo pigment. Approach: Case report: Researchers reported the clinical and histopathologic finding

...more
1 min

MDSpire News

  • November 6, 2026
IFITM1 and CTSS may help identify Sjögren’s dry eye
  • Andrea Surnit
  • November 6, 2026
  • 4 min

Objective: Identify histamine-related genes associated with Sjögren’s syndrome–related keratoconjunctivitis sicca (KCS) and assess their potential diagnostic va

...more
2 min

MDSpire News

  • November 6, 2026
4 societies align on 2026–2027 respiratory vaccine guidance
  • Teraya Smith
  • November 6, 2026
  • 3 min

Objective: The article examines the objective, findings, and clinical context described in 4 societies align on 2026–2027 respiratory vaccine guidance. Approach

...more
2 min

MDSpire News

  • November 6, 2026
Prenatal wildfire smoke linked to autism risk
  • Andrea Surnit
  • November 6, 2026
  • 4 min

Objective: To assess associations between prenatal exposure to wildfire-related fine particulate matter (PM2.5) and childhood autism spectrum disorder (ASD) and

...more
2 min

Phoenix Children's Medical Connection

  • November 6, 2026
Infant Hemispherectomy for Hemimegalencephaly: Why Early Referral Matters
  • November 6, 2026
  • 8 min
  1. Hemimegalencephaly is rare and often causes catastrophic, drug-resistant epilepsy involving most of the affected hemisphere.
  2. Persistent seizures despite two appropriately dosed and tolerated medications, or seizures with an abnormal MRI finding, warrant prompt evaluation at a specialized pediatric epilepsy center.
  3. Intractable epilepsy is an independent risk factor for developmental delay and sudden unexpected death in epilepsy, supporting early imaging and referral.
  4. Hemispherectomy remains the gold standard treatment for HME-associated epilepsy, and surgery may be considered in infancy at experienced centers.
  5. At Phoenix Children’s, fewer than 15% of hemispherectomy patients require a shunt for postoperative hydrocephalus.
...more

MDSpire News

  • November 6, 2026
4 in 10 miss drowsy driving warnings
  • Teraya Smith
  • November 6, 2026
  • 3 min
  1. The National Sleep Foundation estimated that 145 million US adult drivers (61%) have driven while sleepy at least once, and nearly 35 million do so at least monthly.
  2. Approximately 40% of adult drivers do not recognize basic signs of sleep-related impairment, including excessive blinking, head-nodding, and lane drifting.
  3. The report cited AAA Foundation for Traffic Safety data indicating that drowsy driving contributes to approximately 1 in 5 fatal motor vehicle crashes.
  4. Although 58% of adults were familiar with driver-alertness monitoring technology, 31% had used it and 62% worried that collected information could be misused.
  5. The NSF recommends 7 to 9 hours of nightly sleep for most adults and advises sleepy drivers to stop safely, take a break, or arrange alternative transportation.
...more

MDSpire News

  • November 6, 2026
The hidden safety risks of permanent DST
  • Andrea Surnit
  • November 6, 2026
  • 4 min

Objective: To estimate how permanent daylight-saving time (DST) would affect children’s pre-sunrise school commutes and examine the association between morning

...more

The Pathologist

  • November 6, 2026
Flushing Out the Truth in Health Data
  • Christopher Zahner
  • Aakash Bhatia
  • November 6, 2026
  • 10 min
  1. The authors plan to compare a smart toilet’s hydration measurements, based on urine color and concentration, with conventional laboratory methods, including osmolality.
  2. The device is marketed for general wellness and tracks stool patterns, hydration, urinary flow, and bathroom habits.
  3. The article notes that frequent measurements can feel persuasive, but repetition does not establish accuracy.
  4. Laboratory results can be wrong because of unsuitable conditions, poor methods, quality-control failures, reagent changes, matrix effects, software changes, or interferences.
  5. As consumer devices produce measurements resembling established medical tests, clinicians and health systems will need to assess how much trust those measurements deserve.
...more

The Pathologist

  • November 6, 2026
Genomics Reveals Causes of Cerebral Palsy
  • November 6, 2026
  • 2 min

Objective: Assess the diagnostic yield and clinical impact of whole genome sequencing (WGS) in children with cerebral palsy. Approach: Participants and testing:

...more
2 min

The Medicine Maker

  • November 6, 2026
Video: The Ultimate in Translational Medicine – with Harold Keer
  • November 6, 2026
  • 1 min

Objective: The article examines the objective, findings, and clinical context described in Video: The Ultimate in Translational Medicine – with Harold Keer. App

...more
2 min

Jama Network Open

  • November 6, 2026
Correction to the Analysis of Hematopoietic Cell Transplant Access and Patient Diversity
  • November 6, 2026

Objective: The article examines the objective, findings, and clinical context described in Correction to the Analysis of Hematopoietic Cell Transplant Access an

...more
1 min

Jama Network Open

  • November 6, 2026
Long-Term Immune Response and Safety After RSV Vaccination in High-Risk Transplant Recipients
  • Victoria G. Hall
  • Adrian A. Alexander
  • Madeline R. Kern-Smith
  • Faranak Mavandadnejad
  • Sarayna Bala
  • Xiaoqing Dang
  • Rujun Kang
  • Sapna Humar
  • Poramed Winichakoon
  • Rochelle Johnstone
  • Ailya Salman
  • Meghan Aversa
  • Igor Novitzky-Basso
  • Roni Bitterman
  • Pascal M. Lavoie
  • Deepali Kumar
  • Jonas Mattsson
  • Victor H. Ferreira
  • November 6, 2026

Objective: To assess humoral and cell-mediated immune responses and 12-month safety after adjuvanted RSVPreF3 vaccination in lung and allogeneic hematopoietic c

...more
2 min

Jama Network Open

  • November 6, 2026
Putting Unexpected Safety Findings for Overactive Bladder Treatments in Context
  • Sudeep S. Gill
  • November 6, 2026

Objective: The article examines whether exposure to overactive bladder treatments, including β3 adrenergic agonists and anticholinergic medications, is associat

...more
2 min

Jmir Medical Informatics

  • November 6, 2026
Correction: Machine Learning Model for Estimating Overactive Bladder Risk in US Women Using NHANES Data From 2011–2018
  • Guoqiang Huang
  • Shuangquan Lin
  • November 6, 2026

Get quick, clinically relevant Q&A that turns long-form articles into clear answers for faster learning and discovery.

Take the Quiz

Critical Care

  • November 6, 2026
Respiratory Tract Herpesvirus Reactivation in Critically Ill Patients: An Underrecognized Clinical Concern
  • Zhihui Zhang
  • Xuesong Liu
  • Rong Zhang
  • Dongdong Liu
  • Ying Pan
  • Chun Yang
  • Sibei Chen
  • Ling Sang
  • Yimin Li
  • Xiaoqing Liu
  • November 6, 2026

Objective: The article examines the objective, findings, and clinical context described in Respiratory Tract Herpesvirus Reactivation in Critically Ill Patients

...more

Jama Network Open

  • November 6, 2026
AI Scribes and Same-Day Clinical Note Completion Across Patient Language Preferences and Interpreter Use
  • Jorge A. Rodriguez
  • Stuart R. Lipsitz
  • Gezzer Ortega
  • Jacqueline G. You
  • Rebecca G. Mishuris
  • Lipika Samal
  • November 6, 2026

Get a concise, at-a-glance scorecard that distills clinical guidelines into key recommendations, patient insights, and treatment considerations.

View Scorecard

Jama Network Open

  • November 6, 2026
Patterns of Fragile X Syndrome Diagnosis in a Population-Based Cohort Across Multiple States
  • Manish Ghimire
  • Michelle Curtin
  • Stephen Downs
  • Arezoo Movaghar
  • November 6, 2026

Objective: Estimate Fragile X syndrome (FXS) diagnosis rates in a multistate population and assess differences by sex and race. Approach: Design and data: Cross

...more
2 min