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November 5, 2026

Medical Oddities: A needle in an abdominal haystack

Teraya Smith
November 5, 2026
6 min

Objective: The article summarizes four reports: a migrating abdominal sewing needle, urban cooking emissions, tea drinking and vascular disease, and a proposed

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2 min

The Medicine Maker

November 5, 2026

Preparing Community Hospitals for CAR T’s Expansion

Kevin J. Land
November 5, 2026
7 min

Community hospitals grew from 23% to 45% of the US cell and gene therapy administering network between 2018 and 2025, while claims volume rose about 740%.
As CAR T expands to earlier cancer treatment and other diseases, care delivery is expected to become more decentralized and involve coordinated local and specialty providers.
Community hospitals can support diagnosis, referrals, collections, shared care, recovery monitoring, and long-term follow-up without duplicating specialized therapy-center infrastructure.
Community participation can progress from clinician education and referral pathways to toxicity readiness and, where appropriate, active support for therapy delivery.
Partnerships with established therapy programs, collection organizations, laboratories, and manufacturers can provide specialized expertise and infrastructure for community hospitals.

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Intensive Care Medicine

November 5, 2026

Vasopressors and Immune Regulation: An Underrecognized Pathway in Septic Shock

Daniel E. Leisman
Matthijs Kox
Peter Pickkers
November 5, 2026

Get a concise, at-a-glance scorecard that distills clinical guidelines into key recommendations, patient insights, and treatment considerations.

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Intensive Care Medicine

November 5, 2026

Vibroacoustic Music Therapy for Postoperative Delirium in Intensive Care: A Single-Center Exploratory Randomized Controlled Trial (VIMUD-ICU)

Petra Burzlaff
Philipp Simon
Peter Michael von der Nahmer
Susanne Metzner
Philipp Deetjen
November 5, 2026

Objective: To assess therapist-guided vibroacoustic music therapy in non-ventilated adult ICU patients with postoperative delirium. Approach: Design and partici

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2 min

The Analytical Scientist

November 4, 2026

A Manifesto for Modern Food Quality

November 4, 2026
11 min

Get quick, clinically relevant Q&A that turns long-form articles into clear answers for faster learning and discovery.

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The Pathologist

November 4, 2026

Faster Genomic Testing for Children With Cancer

Helen Bristow
November 4, 2026
3 min

Objective: The article reports on Addenbrooke’s Hospital’s use of rapid whole-genome sequencing (WGS) for children suspected of having cancer and discusses how

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2 min

MDSpire News

November 4, 2026

Incidence of flatfoot after peroneuslongus ACL grafting

Andrea Surnit
November 4, 2026
4 min

Objective: To assess new-onset flatfoot after ACL reconstruction using peroneus longus tendon autografts and examine associated factors. Approach: Design and pa

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2 min

MDSpire News

November 4, 2026

Low PET uptake may mask aortic sarcoma

Andrea Surnit
November 4, 2026
3 min

Objective: To describe diagnostic challenges and clinical course in a patient with myxoid aortic intimal sarcoma. Approach: Case: A 69-year-old man with abdomin

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2 min

The Analytical Scientist

November 4, 2026

Thyra Opens MSI to Multimodal Analysis

November 4, 2026
3 min

Objective: The article examines the objective, findings, and clinical context described in Thyra Opens MSI to Multimodal Analysis. Approach: Data conversion: Th

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2 min

MDSpire News

November 4, 2026

Nutritional markers differ in arthroplasty risk

Andrea Surnit
November 4, 2026
4 min

A systematic review of 58 studies involving 2,076,289 patients found that nutritional disorders were associated with adverse outcomes after hip and knee arthroplasty.
Frailty was associated with higher mortality, more postoperative complications and infections, and longer hospital stays across arthroplasty populations.
ESPEN-defined malnutrition was associated with increased mortality, postoperative pain, and longer hospital stays.
Sarcopenia was associated with adverse outcomes, including prosthetic joint infection and poorer functional outcomes.
Associations varied by nutritional measure, and study heterogeneity and risk of bias prevented meta-analysis.

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The Pathologist

November 4, 2026

Colorectal Cancer Diagnosed Too Late in Youth

November 4, 2026
2 min

Objective: To describe disease stage, symptoms, tumor characteristics, recurrence, and outcomes among patients aged 21 or younger diagnosed with colorectal canc

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2 min

The Medicine Maker

November 4, 2026

Who Funds Biotech Shapes What Gets Built

Kathryn Wighton
James Strachan
November 4, 2026
11 min

Get quick, clinically relevant Q&A that turns long-form articles into clear answers for faster learning and discovery.

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The Medicine Maker

November 4, 2026

Naive-Like T Cells Linked to CAR T Durability

November 4, 2026
3 min

Objective: Assess whether CAR T cell product characteristics are associated with outcomes in patients with non-Hodgkin lymphoma. Approach: Primary analysis: Res

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2 min

Jama Network Open

November 4, 2026

Bringing Machine Learning–Based Delirium Risk Prediction Into Clinical Practice: Beyond Discrimination Metrics

Sandeep R. Pagali
Christopher R. Carpenter
November 4, 2026

Objective: Assess whether a fixed multimodal machine-learning model for delirium risk could be implemented at a second hospital without retraining, and describe

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2 min

Jama Network Open

November 4, 2026

Anabolic-Androgenic Steroid Use and Myocardial Flow Reserve in Women

Anders Kløve Petz
Yeliz Bulut
Niels Brandt-Jacobsen
Jon Jarløv Rasmussen
Jan Frystyk
Philip Hasbak
Caroline Kistorp
November 4, 2026

Objective: To examine whether current or former anabolic-androgenic steroid (AAS) use is associated with coronary microcirculation in women. Approach: Design an

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2 min

Jama Network Open

November 4, 2026

Telemedicine Use and Cardiology Service Utilization in the Post-COVID-19 Era

Scott D. Casey
Matthew D. Solomon
Andrew W. Huang
Alan S. Go
Madeline J. Somers
Jie Huang
Andrea K. Millman
Elisha A. Garcia
Deborah Low
Douglas W. Roblin
Mary E. Reed
November 4, 2026

Objective: To compare telemedicine and in-person initial cardiology visits for subsequent health care utilization and time to cardiovascular diagnosis among adu

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2 min

Journal Of General Internal Medicine

November 4, 2026

The National Residency Matching Program Amid Uncertainty

Philip A. Gruppuso
Barak Richman
Eli Y. Adashi
November 4, 2026

Objective: The article examines the objective, findings, and clinical context described in The National Residency Matching Program Amid Uncertainty. Approach: P

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3 min

Critical Care

November 4, 2026

Interpreting the Gastrointestinal Dysfunction Score in Clinical Practice

Qingdong Jia
Minjie Yuan
Shuyi Chen
Kapungo Faith
Caibao Hu
November 4, 2026

Objective: To discuss how measurement practices affect the bedside interpretation of the Gastrointestinal Dysfunction Score (GIDS), evaluated in a prospective m

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2 min