Objective: To provide expert insights into CPS scoring in challenging cases across different indication types. Key Findings: Indication-specific staining charac
Acute ischemic ocular events (IOEs), such as retinal artery occlusion (RAO) and amaurosis fugax, are critical indicators of potential cerebrovascular events, as
Nocturia, prevalent among prostate cancer survivors, significantly impacts quality of life and increases mortality compared to the general population. Current t
Dr. Muhammad Rafiqul Islam emphasizes the significance of patient perceptions in healthcare, particularly in resource-constrained environments like Bangladesh.
Gerald Hsu, MD, PhD, has been appointed as the new Editor-in-Chief of the ASCO Educational Book, bringing a wealth of experience as a Professor of Clinical Medi
The National Academy of Medicine has elected new members recognized for their significant contributions to health and medicine, highlighting achievements in adv
Utah's pilot program allows AI to autonomously renew prescriptions for chronic conditions, showcasing legal and ethical implications, particularly in oncology s
Survivors of childhood cancer who reach age 50 face increased risks for premature mortality, subsequent cancers, and chronic conditions, significantly higher th
In a pivotal phase III trial (KEYNOTE-905), combining enfortumab vedotin-ejfv, an antibody-drug conjugate, with the PD-1 inhibitor pembrolizumab significantly e
A recent longitudinal cohort study by Glen et al., published in JACC: CardioOncology, highlights the prevalence of cancer therapy-related cardiac dysfunction an
The CLIMATE study evaluates miR-371a-3p as a novel biomarker for identifying patients with stage I testicular cancer who may require adjuvant therapy after orch
The ACROBAT study revealed that the AI-powered AlloHeme tool significantly improves relapse prediction in patients with acute myeloid leukemia (AML) and myelody
Circulating tumor DNA (ctDNA) testing for early breast cancer shows potential but lacks interventional trial support to confirm improved patient outcomes. Accor
The phase III LITESPARK-011 trial revealed that the combination of belzutifan, a novel HIF-2α inhibitor, with lenvatinib significantly improved progression-free
Recent advancements in the treatment of advanced pancreatic cancer have emerged, particularly with the development of daraxonrasib, a potent inhibitor targeting
Objective: To assess the stroke risk following acute ischemic ocular events (IOEs) and their implications for systemic health, emphasizing the critical nature o
Objective: To review the transgenerational impacts of BPA exposure on male infertility risk and the specific roles of gut microbiota interactions within the gut
Objective: To present a case of parathyroid carcinoma manifesting as hyperparathyroidism in a young male, emphasizing the need to recognize endocrine causes in
Parathyroid carcinoma is a rare malignant tumor, accounting for approximately 0.005% of all malignancies and a rare cause of primary hyperparathyroidism.
A 36-year-old man presented with a pathological fracture after minimal trauma, highlighting an atypical initial manifestation of parathyroid carcinoma.
Laboratory evaluation revealed severe hypercalcemia and markedly elevated parathyroid hormone levels, consistent with primary hyperparathyroidism.
Surgical resection confirmed the diagnosis of parathyroid carcinoma, emphasizing the need for careful evaluation in cases of unexplained hypercalcemia.
This case underscores the importance of considering endocrine causes in patients with pathological fractures and recurrent nephrolithiasis.