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What is MDSpire?

MDSpire is an innovative platform aiming to create a smarter, faster, and more connected medical community.

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June 26, 2026

Surveillance May Reduce CIN 2 Overtreatment

Andrea Surnit
June 26, 2026
3 min

Summary
Insight Report
Quiz

Objective: To evaluate whether surveillance can reduce unnecessary excisions in patients with cervical intraepithelial neoplasia grade 2 (CIN 2) without increas

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The Medicine Maker

June 26, 2026

Biopharma Vital Signs – Part 2: Emerging Trends

June 26, 2026
10 min

Summary
Insight Report
Quiz
Clinical Scorecard

Objective: To explore current trends shaping the development, manufacturing, and commercialization strategies in the biotech and biopharma industries. Approach:

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The Medicine Maker

June 26, 2026

Biopharma Vital Signs – Part 2: Emerging Trends

June 26, 2026
7 min

Summary
Insight Report
Quiz

Objective: To explore current trends shaping the development, manufacturing, and commercialization in biotech and biopharma. Approach: Industry Insights: Indust

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June 26, 2026

Can AI Extract Echo Report Data as Accurately as Expert Annotation?

Kerri Miller
June 26, 2026
5 min

Summary
Insight Report
Poll
Topic Commentary

Objective: To evaluate the accuracy of a large language model (GPT-5 mini) in extracting structured cardiovascular data from free-text echocardiography reports.

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June 26, 2026

Does Mitral Regurgitation Mechanism Matter After M-TEER?

Kathryn Wighton
June 26, 2026
3 min

Summary
Insight Report
Poll
Topic Commentary

Objective: To evaluate the changes in left ventricular diameters and hemodynamics across different mitral regurgitation mechanisms following mitral transcathete

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June 26, 2026

Pilot Study Assesses AI-Guided Cardiac Ultrasound

Kathryn Wighton
June 26, 2026
3 min

Summary
Takeaways
Insight Report
Quiz
Poll
Clinical Scorecard

Objective: To evaluate the effectiveness of artificial intelligence (AI) guidance in cardiac point-of-care ultrasound performed by advanced practice providers.

AI-guided cardiac point-of-care ultrasound showed high agreement with cardiologist reviews, with over 96% agreement on major findings.
Cardiologists corrected 27% of AI-guided examinations, compared to 47% of non-AI-guided examinations, indicating fewer errors.
Scan duration was shorter with AI guidance, averaging 13.7 minutes versus 16.9 minutes without AI assistance.
Point-of-care ultrasound findings led to management changes in 57% of patients, primarily affecting fluid or diuretic therapy.
56% of patients were discharged without needing inpatient transthoracic echocardiography, highlighting efficiency in patient management.

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The Ophthalmologist

June 26, 2026

AI: From Hype to Real-World Clinical Value

Kai Jin
Andrzej Grzybowski
June 26, 2026
13 min

Summary
Insight Report
Quiz
Topic Commentary

Objective: To examine the real-world clinical value of AI in ophthalmology, moving beyond technical novelty to assess its impact on eye care delivery. Approach:

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June 26, 2026

What Changes Under 2025 ASE Diastolic Function Criteria?

Kathryn Wighton
June 26, 2026
2 min

Summary
Takeaways
Insight Report
Quiz
Poll
Clinical Scorecard

Objective: To evaluate the impact of the 2025 American Society of Echocardiography diastolic function grading guidelines compared to the 2016 guidelines. Approa

20.1% of echocardiograms received different diastolic function grades when evaluated using the 2016 and 2025 ASE guidelines.
The study analyzed 300,828 adult transthoracic echocardiograms performed between 2013 and 2022.
Under the 2025 guidelines, 14.0% of studies were upgraded in diastolic dysfunction grading compared to the 2016 guidelines.
The proportion of studies classified as having normal diastolic function decreased from 78.9% under 2016 to 73.8% under 2025.
Older age, female sex, and higher left ventricular systolic function were associated with increased diastolic dysfunction grading using the 2025 guidelines.

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June 26, 2026

ASE Plenary: Progress, Priorities, and What’s Next

Julia Cipriano, MS, CMPP
June 26, 2026
4 min

Summary
Insight Report
Poll
Topic Commentary

Objective: To reflect on the American Society of Echocardiography's accomplishments during the 2026 Scientific Sessions and discuss future initiatives. Approach

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The Pathologist

June 26, 2026

Doing More With Every Biopsy

Jessica Allerton
June 26, 2026
7 min

Summary
Insight Report
Poll
Topic Commentary

Objective: To explore the challenges in tissue utilization in oncology and the potential of virtual staining to enhance tissue analysis while preserving samples

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The Pathologist

June 26, 2026

Teaching AI to Read Liquid Biopsies

June 26, 2026
2 min

Summary
Insight Report
Quiz
Topic Commentary

Objective: To evaluate the ability of large language models (LLMs) to identify diagnostic biomarkers from cell-free RNA (cfRNA) data. Approach: Study Design: Re

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The Ophthalmologist

June 26, 2026

New CEO for Optos

June 26, 2026
2 min

Summary
Insight Report
Poll

Objective: To announce the appointment of Alexandre Montague as the new CEO of Optos. Approach: Leadership Experience: Montague has nearly 25 years of leadershi

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The Ophthalmologist

June 26, 2026

Photosynthesis Comes to the Cornea

June 26, 2026
3 min

Summary
Insight Report
Poll
Clinical Scorecard

Objective: To explore the potential of transplanting plant light-harvesting machinery into mammalian eye cells to enable the cornea to generate its own light-dr

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The Analytical Scientist

June 26, 2026

Leading with Purpose: Sitting Down With Shane Needham

James Strachan
June 26, 2026
8 min

Summary
Takeaways
Insight Report
Poll

Objective: To explore Shane Needham's journey as a scientist, entrepreneur, and leader, and how his experiences shape his business philosophy. Approach: Backgro

Shane Needham has founded 11 businesses and emphasizes the importance of a strong founding team for success.
He believes in hiring for attitude and coachability, valuing resilience and personal challenges in team members.
Needham's motto, "never be outworked," reflects his dedication and work ethic developed through bodybuilding and sports.
He maintains a structured schedule to balance multiple commitments, prioritizing family time alongside work.
Needham's faith influences his business decisions, guiding his vision to glorify God and leave a legacy for his family.

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Frontiers In Hematology

June 26, 2026

Crosstalk of factors underlying bone marrow niche-mediated chemoprotection in acute myeloid leukemia

Shah, Arunim
Chaturvedi, Chandra
Trivedi, Arun Kumar
June 26, 2026

Summary
Quiz
Clinical Scorecard

Objective: To outline key cellular and molecular mechanisms underlying AML–niche interactions and their role in chemoresistance. Approach: Review of Mechanisms:

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Frontiers In Neurology

June 26, 2026

Endolymphatic hydrops in patients with migraine: a correlative study

Anne R. J. Péporté
Fabian Schön
Gustav Andreisek
Jatta Berberat
Franca Wagner
June 26, 2026

Summary
Insight Report
Quiz
Poll
Clinical Scorecard

Objective: To examine MRI correlations between endolymphatic hydrops (EH) severity and migraine brain biomarkers. Approach: Study Design: Retrospective review o

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Get a concise, at-a-glance scorecard that distills clinical guidelines into key recommendations, patient insights, and treatment considerations.

Get quick, clinically relevant Q&A that turns long-form articles into clear answers for faster learning and discovery.

Share your perspective with a quick, clinically relevant poll that captures real-world insights and clinician sentiment.

Frontiers In Neurology

June 26, 2026

Serum uric acid-to-HDL cholesterol ratio and stroke prevalence: NHANES 1999–2018 with external support from an imaging-confirmed hemorrhagic stroke dataset

Tiansheng Su
Yong Mo
Guangxiang Huang
Jiachao Lu
Shuling Tang
Qin Hu
Qianrong Huang
Fangzhou Guo
Ligen Mo
Jun Yan
June 26, 2026

Summary
Insight Report
Quiz
Topic Commentary

Objective: To investigate the association between the uric acid to high-density lipoprotein cholesterol ratio (UHR) and prevalent stroke using NHANES data. Appr

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Frontiers In Oncology

June 26, 2026

Quercetagetin-rich flavonoids from marigold induce apoptosis inhibit metastasis of non-small cell lung cancer via the p53/p21 signaling pathway

Zhihuan Dong
Xinying Cheng
Yunhe Lian
Di Wu
Kaihui Liu
Xue Feng
Qiang Xue
Qingliang Chen
Limin Wang
June 26, 2026

Summary
Insight Report
Poll
Clinical Scorecard

Objective: To investigate the in vitro and in vivo inhibitory effects of quercetagetin-rich marigold flavonoids (QG-MF) on non-small cell lung cancer (NSCLC). A

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Get a concise, at-a-glance scorecard that distills clinical guidelines into key recommendations, patient insights, and treatment considerations.

Share your perspective with a quick, clinically relevant poll that captures real-world insights and clinician sentiment.

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