MDSpire - MDSpire Home
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

International Journal Of Colorectal Disease

  • October 28, 2026
Correction: Long-term outcomes of gracilis muscle transposition for 60 complex anorectal fistulas of varied types and causes
  • Mila Isabelle Schoene
  • Sabine Schatz
  • Marion Brunner
  • Alois Fuerst
  • October 28, 2026

Objective: To correct the first author’s given name and the author-contributions section. Approach: Correction: The notice states that Mila is the first author’

...more

The Analytical Scientist

  • October 28, 2026
Two Combs, One Detailed Molecular Picture
  • October 28, 2026
  • 3 min

Objective: Review developments in dual-comb spectroscopy in the mid-infrared and terahertz regions and compare technologies used to generate frequency combs. Ap

...more
2 min

The Analytical Scientist

  • October 28, 2026
Raman Spectroscopy Distinguishes SARS-CoV-2 Variants
  • October 28, 2026
  • 3 min

Objective: To assess whether Raman spectroscopy with spectral barcoding can distinguish RNA from SARS-CoV-2 variants and subvariants. Approach: Samples: Researc

...more
2 min

MDSpire News

  • October 27, 2026
Endometrial cancer drug cuts progression or death risk 41%
  • Mouj Hijazi
  • October 27, 2026
  • 3 min

Objective: To compare sacituzumab tirumotecan with physician’s-choice chemotherapy in previously treated advanced or recurrent endometrial cancer. Approach: Des

...more
3 min

MDSpire News

  • October 27, 2026
FDA expands talazoparib use in prostate cancer
  • Mouj Hijazi
  • October 27, 2026
  • 3 min

Objective: The article examines the objective, findings, and clinical context described in FDA expands talazoparib use in prostate cancer. Approach: Approval: T

...more

MDSpire News

  • October 27, 2026
AMD incidence may be higher in lupus
  • Andrea Surnit
  • October 27, 2026
  • 4 min
  1. In a South Korean claims-based cohort, 9,496 adults aged 45 years or older with incident SLE were matched with 28,488 controls and followed for a mean of 6.7 and 7 years, respectively.
  2. Overall AMD incidence was 49.1 per 10,000 person-years among patients with SLE and 26.7 among controls.
  3. Neovascular AMD incidence was 10.5 per 10,000 person-years in patients with SLE and 3.3 in controls; dry AMD incidence was 38.6 and 23.4, respectively.
  4. Treatment-defined severe SLE was not associated with significantly higher incidence of overall, dry, or neovascular AMD than nonsevere SLE.
  5. Although neovascular AMD likelihood versus controls was higher in both hydroxychloroquine exposure groups, longer exposure was not significantly associated with higher neovascular AMD hazards within t
...more

MDSpire News

  • October 27, 2026
Keratoplasty may salvage severe corneal melt
  • Andrea Surnit
  • October 27, 2026
  • 4 min

Get a concise, at-a-glance scorecard that distills clinical guidelines into key recommendations, patient insights, and treatment considerations.

View Scorecard

MDSpire News

  • October 27, 2026
AI may aid segmental pulmonary embolism detection
  • Andrea Surnit
  • October 27, 2026
  • 4 min

Objective: Assess whether deployment of a commercial AI tool was associated with changes in incidental pulmonary embolism (iPE) reporting on routine contrast-en

...more
2 min

MDSpire News

  • October 27, 2026
CDC chief medical officer resigns after 6 months
  • Teraya Smith
  • October 27, 2026
  • 2 min

Objective: The article reports Jennifer Shuford’s resignation as CDC deputy director and chief medical officer, her stated reason for leaving, and the interim l

...more
2 min

MDSpire News

  • October 27, 2026
4 societies redefine women's heart care
  • Teraya Smith
  • October 27, 2026
  • 3 min

Objective: The article examines the objective, findings, and clinical context described in 4 societies redefine women's heart care. Approach: Developers: The Am

...more

The Analytical Scientist

  • October 27, 2026
Musings from The Power List: Gerrit Renner
  • October 27, 2026
  • 5 min
  1. Gerrit Renner’s research develops data-processing and chemometric approaches that preserve uncertainty, quality, and provenance throughout analytical workflows.
  2. Renner treats data processing as part of analytical measurement, with transparent processing steps and quantitative uncertainty and quality measures.
  3. He argues that machine-actionable analytical data should carry metadata, provenance, uncertainty, and semantic meaning.
  4. Renner says processing decisions can affect results, yet their rationale and uncertainty are often difficult to reconstruct.
  5. He believes FAIR data should be built into analytical workflows from acquisition onward, rather than addressed only at the end of a project.
...more

The Analytical Scientist

  • October 27, 2026
Putting Food Analysis to Work
  • October 27, 2026
  • 5 min
  1. Michele Suman works across Barilla, the Food-ER consortium, and university teaching, connecting academic and applied food research.
  2. Suman is motivated to turn laboratory methods into tools that laboratories, food companies, public organizations, and standards bodies can use.
  3. He argues that sustainability in food science should be substantiated by comprehensive study across the food supply chain.
  4. One study developed an LC-MS method to detect pyrrolizidine and tropane alkaloids in cereals and spices at very low levels and in line with EU requirements.
  5. A second study developed a fast, practical LC-MS screening method for ergot alkaloids in cereal-based products to identify potential contamination before confirmatory analysis.
...more

The Medicine Maker

  • October 27, 2026
Amgen Expands Veeva Partnership
  • October 27, 2026
  • 2 min

Objective: The article examines the objective, findings, and clinical context described in Amgen Expands Veeva Partnership. Approach: Deployment: Amgen plans to

...more
1 min

The Pathologist

  • October 27, 2026
Before the White Coat
  • Kasem Jamil Al-Saloumi
  • October 27, 2026
  • 8 min
  1. Laboratory career education should teach students that instruments generate measurements, while clinical meaning depends on interpreting them in context.
  2. A precise potassium measurement from a hemolyzed specimen may not represent the patient's circulating potassium because red blood cells release intracellular potassium.
  3. A result outside a reference interval is evidence to interpret, not a verdict, because reference intervals commonly include the central 95% of a specified population.
  4. A positive molecular signal does not by itself establish clinical significance; interpretation may depend on the organism, specimen, timing, assay, and other evidence.
  5. Students can learn laboratory reasoning by examining controls, specimen quality, analytical precision, clinical relevance, and alternative explanations, even without using a clinical analyzer.
...more

The Pathologist

  • October 27, 2026
Mitochondrial Diagnoses From Skin Tests
  • October 27, 2026
  • 2 min

Objective: To assess whether combined functional tests on skin fibroblasts can help identify mitochondrial dysfunction, particularly when genomic sequencing is

...more
2 min

The Analytical Scientist

  • October 27, 2026
Inside the $10 Optical Spectrometer
  • October 27, 2026
  • 3 min

Objective: To develop and evaluate a compact, low-cost near-infrared spectrometer for identifying materials and measuring concentrations, and to explore its pot

...more
2 min

Jama Network Open

  • October 27, 2026
Strengthening Hospital Readiness for Future Disasters: Tackling Critical Challenges
  • Dan Hanfling
  • October 27, 2026
  1. COVID-19 exposed hospital vulnerabilities in surge staffing, critical supply chains, patient distribution, crisis standards of care, and health care coalition coordination.
  2. Interviews with 69 informants at 10 safety-net hospitals identified these five domains as challenges to resilience and sustained health care delivery.
  3. The authors attribute preparedness gaps partly to competing financial demands, a false sense of security, and a recurring panic-neglect cycle.
  4. The authors call for stronger, adequately funded health care coalitions and closer integration of patient safety and quality initiatives with emergency planning.
  5. The authors recommend prioritizing medical operations coordinating centers to direct patients to facilities with available resources and improve regional information sharing.
...more

United States Department Of Health And Human Services

  • October 27, 2026
FDA and CMS Outline Initiatives to Support Gene Therapy Development and Improve Access for People with Rare Diseases
  • Assistant Secretary for Public Affairs (ASPA)
  • October 27, 2026

Objective: The article describes FDA draft guidance for submitting and managing BLAs for individualized genome-editing therapies and CMS plans to expand its vol

...more
2 min