Eighty-eight percent of individuals with obesity face stigma affecting their care experience. A new perspective by Miras et al. in Obesity Science & Practice id
Rashmi Sarkar, MD, and Hitaishi Mehta, MD, discuss the limitations of the Fitzpatrick scale in addressing diverse skin types, particularly for darker skin tones
A study published in the International Wound Journal revealed that open-but-unused wound dressings can become contaminated with microbes soon after opening, eve
A French phase III trial, UNICANCER HypoG-01, has revealed that hypofractionated locoregional radiotherapy (RT) at 40 Gy over 3 weeks is noninferior to the stan
In the MajesTEC-3 trial, a combination of teclistamab and daratumumab demonstrated significant efficacy for previously treated multiple myeloma patients, achiev
Encouraging results from the first-in-human trial of in vivo CAR T-cell therapy KLN-1010 for multiple myeloma reflect promising safety and effectiveness, as rep
The FDA has approved setmelanotide (IMCIVREE) as the first treatment for acquired hypothalamic obesity, a condition caused by damage to the hypothalamus affecti
A study from Harvard analyzed data from 25,820 patients, revealing that higher adherence to a healthy lifestyle post-hypertension diagnosis significantly reduce
A phase 2b randomized clinical trial assessed the efficacy of psilocybin-assisted psychotherapy on treatment-resistant depression (TRD) but found no significant
Molecular pathology is evolving to play a crucial role in patient care by transitioning from traditional diagnostic methods to a focus on molecular behavior of
A study in Hepatology reveals a rare inherited variant in the MET gene responsible for steatotic liver disease (SLD) in certain patients, independent of typical
The European Myopia Network (EMN) addresses the rising prevalence of myopia across Europe through a collaborative effort involving over 27 experts from various
Age-related macular degeneration (AMD) significantly impacts vision in individuals over 50. Early intervention is crucial for slowing disease progression and pr
Objective: To characterize the bone marrow hematopoietic compartment and its link to osteoclastogenesis in mouse models of MASLD and MetALD, focusing on specifi
High-fat diet (HFD) depletes hematopoietic stem cells, while HFD plus ethanol (HFD+EtOH) preserves them and skews hematopoiesis toward myeloid progenitors.
HFD+EtOH significantly increases committed osteoclast precursors compared to HFD alone, enhancing osteoclastogenesis and associated bone activity.
Mice on HFD+EtOH exhibit elevated osteoclast activity, increased epiphyseal area, and prolonged growth plate activity, affecting bone structure.
The study highlights the interplay between metabolic dysfunction-related liver diseases and hematopoietic health, emphasizing the need for integrated treatment approaches.
Findings suggest that alcohol exacerbates the effects of a high-fat diet on immune and skeletal health, warranting further research into these interactions.
Objective: To determine the 3-year disease-free survival (DFS) and overall survival (OS) outcomes of the mixed approach vs. the medial approach in laparoscopic
Objective: To assess the impact of AI on radiologist well-being, particularly regarding burnout, workload, and other systemic factors. Key Findings: AI's impact
Objective: To describe the frequency of STIs in patients at a student-run free clinic and compare infection rates between asymptomatic and symptomatic patients,
Objective: Emphasize the systematic nature of the analysis. Key Findings: Include more specific details from the source. Interpretation: Elaborate on clinical i