MDSpire Home

October 19, 2026

FDA approves dostarlimab for advanced rectal cancer

Mouj Hijazi
October 19, 2026
3 min

Objective: The article examines the objective, findings, and clinical context described in FDA approves dostarlimab for advanced rectal cancer. Approach: Approv

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2 min

Phoenix Children's Medical Connection

October 19, 2026

A Real-World Evidence Study on U.S. Patients Demonstrating Safety of High-Frequency Use of the Remote Electrical Neuromodulation (REN) Wearable Device for Migraine Treatment

October 19, 2026
2 min

Objective: To evaluate the safety and tolerability of REN use that exceeded current labeling for migraine treatment. Approach: Study design: Real-world observat

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2 min

Phoenix Children's Medical Connection

October 19, 2026

Molecular and Clinical Spectrum of Epilepsy-Dyskinesia Syndromes: A Cross-Sectional Study of 609 Patients

October 19, 2026
2 min

Objective: To characterize genetic, clinical, developmental, and treatment-response features of epilepsy-dyskinesia syndromes in children. Approach: Study desig

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2 min

MDSpire News

October 19, 2026

Catheter stop orders may be losing ground

Andrea Surnit
October 19, 2026
4 min

Objective: The article examines the objective, findings, and clinical context described in Catheter stop orders may be losing ground. Approach: Design: Repeated

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1 min

The Medicine Maker

October 19, 2026

Three Targets, One CAR T Therapy

October 19, 2026
4 min

Objective: Evaluate the safety, feasibility, and early clinical activity of a CAR T-cell therapy targeting CD19, CD20, and CD22 in patients with relapsed or ref

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2 min

The Medicine Maker

October 19, 2026

Hiring for What Comes Next

Teresa Reti
October 19, 2026
7 min

Objective: The article examines the objective, findings, and clinical context described in Hiring for What Comes Next. Approach: Milestone-focused hiring: Board

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3 min

The Pathologist

October 19, 2026

New Tick-Borne Virus Identified in China

October 19, 2026
3 min

Objective: To identify and characterize a previously unknown tick-borne virus in patients with fever and tick exposure in China. Approach: Patient testing: Rese

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2 min

The Pathologist

October 19, 2026

Introducing The Pathologist Hall of Fame

Helen Bristow
October 19, 2026
4 min

Objective: Introduce a permanent Hall of Fame recognizing individuals whose influence on pathology has endured. Approach: Eligibility: The Hall of Fame recogniz

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2 min

The Analytical Scientist

October 19, 2026

Musings from The Power List: Christopher Rüger

October 19, 2026
13 min

Objective: The article examines the objective, findings, and clinical context described in Musings from The Power List: Christopher Rüger. Approach: Research fo

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3 min

The Analytical Scientist

October 19, 2026

44,000 Protein Forms Mapped in Plasma

October 19, 2026
3 min

Objective: To map the diversity of protein forms (proteoforms) in human plasma and examine how proteoform diversity relates to measurements from affinity-based

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2 min

The Medicine Maker

October 19, 2026

SRSF1 Gene Delivery Extends Lifespan in Aged Mice

October 19, 2026
3 min

Objective: Identify a gene that can make aged cells show younger molecular features while preserving their specialized identity, and test its effects in aged mi

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2 min

Jama Network Open

October 19, 2026

Nativity and Length of US Residence in Relation to Nonadherence to Colorectal Cancer Screening

Sebastian O. Ekenze
Areesh Mevawalla
Aayan E. Kibria
Kizuki Yuza
Abdulaziz Elemosho
Timothy M. Pawlik
October 19, 2026

Objective: Assess whether nativity and duration of US residence were associated with nonadherence to colorectal cancer screening guidelines among US adults aged

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2 min

Jama Network Open

October 19, 2026

Implementing Drug Allocation Policies Amid a Severe Chemotherapy Shortage

Eric C. Blackstone
Yating Wang
Eno-Abasi Inyang
Andrew G. Shuman
Michael Casey
Gregory A. Abel
Andrew Hantel
October 19, 2026

Objective: To evaluate implementation of the Dana-Farber Cancer Institute (DFCI) carboplatin allocation plan and assess whether clinical or demographic factors

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1 min

Journal Of Medical Internet Research

October 19, 2026

Organizational Stakeholders’ Perspectives on Implementing Video Consultations in General Practice: A Qualitative Study of Strategic Considerations

Ulrik Bak Kirk
Ditte Bonde Stanek
Mette Amalie Nebsbjerg
Flemming Bro
Linda Huibers
Adrian Rohrbasser
Anna Mygind
Viola Burau
Ida Hestbjerg
October 19, 2026

Objective: To examine organizational stakeholders’ perspectives on implementing video consultations in general practice, addressing a gap in research focused ma

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1 min

Clinical Research In Cardiology

October 19, 2026

Takotsubo Syndrome Revisited: Findings From a Multicenter Cohort Study

Hugo Lanz
Endrit Cekaj
Lucas Bacmeister
Christian Jung
Samuel Muli
Sabine Hoffmann
Matthias Schmid
Marcelo Galdos-Bejar
Daniel Hoyer
Lisa Crusius
Norman Mangner
Lisa Reinhardt
Loubna Yahsaly
Lars Michel
Victoria Pfeiffer
Mostafa Salem
Rafael Henrique Rangel
Johannes Terporten
Fabian Heindl
Marcus Brugger
Sebastian Zimmer
Tienush Rassaf
David Leistner
Dirk Westermann
Benjamin Meder
Malte Kelm
Stephan Baldus
Christian Schulze
Georg Nickenig
Franz Haertel
Enzo Lüsebrink
October 19, 2026

This retrospective multicenter cohort included adults with Takotsubo syndrome treated at 13 German tertiary care centers from 2013 through 2024.
Patients were classified by acute neurologic, other physical, emotional, or unidentified triggers.
The study examined whether acute brain pathology was associated with cardiac dysfunction severity differently from other physical stressors.
Investigators assessed short-term cardiac recovery and factors associated with a critical in-hospital course.
The composite in-hospital cardiac complication endpoint included atrial fibrillation, ventricular tachycardia or fibrillation, pulmonary edema, cardiogenic shock, and death.

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Jama Network Open

October 19, 2026

At-Home Transcranial Direct Current Stimulation Combined With Gamified Cognitive Control Training for Depression: A Study

Esther Dechantsreiter
Frank Padberg
Yuval Benjamini
Stephan Goerigk
Linda Rubene-Kesele
Liene Konosonoka
Ulrike Vogelmann
Tamar Cohen
Naamah Lerner
Gerrit Burkhardt
Aldo Soldini
Fabienne Windel
Marios Fanourakis
Zeno Menestrina
Arthur Nguyen
Angela Pasqualotto
Takuya Morishita
Amir Dotan
Shira Ahissar
Alon Morash
Jonas Björklund
Lucia Bulubas
Daniel Keeser
Netta Assa
Rémy Gardier
Roser Viñals
Jean-Philippe Thiran
Ronen Segman
Omer Bonne
Amit Lotan
Friedhelm C. Hummel
Elmars Rancans
Daphne Bavelier
Mor Nahum
October 19, 2026

Objective: To assess the feasibility, safety, and efficacy of home-based transcranial direct current stimulation (tDCS) combined with gamified cognitive control

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1 min

Intensive Care Medicine

October 19, 2026

Recent Updates in Point-of-Care Lung Ultrasound: Interpreting the New Recommendations

Giovanni Volpicelli
Luna Gargani
Laurent Zieleskiewicz
October 19, 2026

Objective: The commentary identifies what is new in two recent evidence-based publications on lung ultrasound and explains the purpose and limits of their forma

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1 min

United States Department Of Health And Human Services

October 19, 2026

Trump Signs Executive Order to Expand Women’s Health Research, With First Lady Melania Trump’s Support

Assistant Secretary for Public Affairs (ASPA)
October 19, 2026

Objective: The article examines the objective, findings, and clinical context described in Trump Signs Executive Order to Expand Women’s Health Research, With F

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2 min