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Obesity Surgery

  • October 24, 2026
Correction: Comparing Sleeve Gastrectomy and Roux-en-Y Gastric Bypass in Obese Kidney Transplant Candidates: Systematic Review, Meta-Analysis, and a Transplant-Specific Decision Framework
  • Hany El Hennawy
  • Omar Safar
  • Ghaleb Aboalsamh
  • Mostafa Marzouk
  • Menna El Hennawy
  • Abdullah Khedr
  • Ahmed Sharab
  • Abdullah Alharthi
  • Ramiz Aesh
  • Tariq Jaber
  • October 24, 2026

Objective: Correct an omitted author affiliation in the original article. Approach: Correction: Affiliation number 10 identifies Tariq Jaber’s institution as Ki

...more
1 min

MDSpire News

  • October 23, 2026
FDA raises TMB threshold for pembrolizumab
  • Mouj Hijazi
  • October 23, 2026
  • 3 min

Objective: The article examines the objective, findings, and clinical context described in FDA raises TMB threshold for pembrolizumab. Approach: Regulatory deci

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MDSpire News

  • October 23, 2026
H2-blocker tachyphylaxis may limit LPR therapy
  • Andrea Surnit
  • October 23, 2026
  • 4 min

Objective: Review evidence on H2-receptor antagonists for laryngopharyngeal reflux (LPR), including tolerance with continuous use and their role in current mana

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2 min

MDSpire News

  • October 23, 2026
FDA clears at-home risankizumab induction
  • Teraya Smith
  • October 23, 2026
  • 2 min

Objective: The article examines the objective, findings, and clinical context described in FDA clears at-home risankizumab induction. Approach: Approval: The FD

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2 min

MDSpire News

  • October 23, 2026
Caffeine may be tied to lower cortical surface area
  • Andrea Surnit
  • October 23, 2026
  • 5 min

Objective: To examine associations between adolescents’ caffeine consumption, sleep duration, cortical structure, and later mental health problems. Approach: Pa

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2 min

MDSpire News

  • October 23, 2026
Fulminant GBS may mimic brain death
  • Andrea Surnit
  • October 23, 2026
  • 6 min

Get quick, clinically relevant Q&A that turns long-form articles into clear answers for faster learning and discovery.

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MDSpire News

  • October 23, 2026
Lupus nephritis may remit despite HIV
  • Andrea Surnit
  • October 23, 2026
  • 4 min

Objective: To describe renal and HIV outcomes during immunosuppressive treatment for biopsy-confirmed lupus nephritis in a patient with HIV. Approach: Case: Res

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2 min

MDSpire News

  • October 23, 2026
IOL exchange may ease postcataract dizziness
  • Andrea Surnit
  • October 23, 2026
  • 4 min

Objective: To assess whether restoring habitual myopia could relieve persistent dizziness and visual discomfort after cataract surgery in a patient with strong

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2 min

The Pathologist

  • October 23, 2026
The Search for a Sepsis Signal
  • Helen Bristow
  • October 23, 2026
  • 10 min

Objective: The article discusses limitations of current sepsis diagnosis, the potential role of emerging biomarkers in risk stratification, and challenges in tr

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The Pathologist

  • October 23, 2026
Could Wearables Redefine Diagnostics?
  • October 23, 2026
  • 2 min

Objective: Review developments in wearable diagnostic systems and assess their potential applications and barriers to clinical use. Approach: Scope: The review

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2 min

The Medicine Maker

  • October 23, 2026
Live Roundtable: What Is the Biggest Bottleneck Holding Back Cell and Gene Therapy?
  • October 23, 2026
  • 1 min

Objective: Present expert perspectives on the main barriers to making cell and gene therapies widely accessible and where the industry should focus its efforts.

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1 min

Critical Care

  • October 23, 2026
Response to “Left Ventricular Longitudinal Function and Hyperkinetic Profile: A New Echocardiographic Area for Exploration?”
  • Oscar Cavefors
  • Jonatan Oras
  • October 23, 2026
  1. In exploratory post hoc analyses, 90-day mortality was 27% with LVEF >70% and 23% with LVEF 50%–70%, with no significant adjusted difference.
  2. Patients with LVEF >70% had greater absolute GLS magnitude and modestly higher MAPSE than those with LVEF 50%–70%; S′ did not differ significantly.
  3. No distinct MAPSE, GLS, or S′ threshold corresponding to a hyperdynamic LVEF profile was identified.
  4. High-value GLS, MAPSE, and S′ groups were not associated with 90-day mortality in unadjusted or adjusted analyses.
  5. The exploratory findings suggest hyperdynamic LVEF may not reflect a comparably hyperdynamic longitudinal systolic profile and warrant cautious interpretation.
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Jama Network Open

  • October 23, 2026
Neighborhood Disadvantage and Disparities in Atrial Fibrillation Detection
  • Kamala P. Tamirisa
  • Larry R. Jackson
  • October 23, 2026

Objective: To assess whether neighborhood disadvantage is associated with differences in atrial fibrillation (AF) diagnosis and treatment. Approach: Population

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United States Department Of Health And Human Services

  • October 23, 2026
ACL Selects 70 Phase 1 Winners in Challenge to Make Community Gardens More Accessible
  • Administration for Community Living (ACL)
  • October 23, 2026
  1. On October 23, 2026, ACL named 70 Phase 1 winners in the nationwide Cultivating Connected Communities Prize Challenge.
  2. Teams from 37 states and Tribal communities proposed ways to improve community garden access for people with disabilities and older adults.
  3. A multidisciplinary expert panel selected winners based on accessibility strategies, sustainability, and community partnerships.
  4. Each Phase 1 winner will receive $4,000 and may advance to Phase 2 to implement plans and monitor outcomes.
  5. Phase 2 proposals are due by May 2027, and teams may receive an additional prize of up to $8,000 based on implementation results.
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Jmir Medical Informatics

  • October 23, 2026
Travel Distance Between Patients and Providers for Medicare Outpatient Oncology Telehealth and Office Visits, 2021–2023: A Cross-Sectional Claims Study
  • Lingbo Liu
  • Tracy Onega
  • Erika L Moen
  • Anna N A Tosteson
  • Rebecca E Smith
  • Qianfei Wang
  • Lauren Cowan
  • Fahui Wang
  • October 23, 2026

Get a concise, at-a-glance scorecard that distills clinical guidelines into key recommendations, patient insights, and treatment considerations.

View Scorecard

Jama Network Open

  • October 23, 2026
Profile and Financial Impact of Measures Dropped From Medicare Advantage Star Ratings
  • Derek T. Lake
  • Yasin Civelek
  • Amelia M. Bond
  • Dhruv Khullar
  • October 23, 2026
  1. The analysis included 425 Medicare Advantage contracts covering 29.0 million enrollees and evaluated 13 components of 11 measures removed from 2026 Star Ratings.
  2. Only 5 of the 13 removed measures were topped out, while none of the 30 retained measures met the study’s topping-out definition.
  3. Removed measures had higher average scores than retained measures, but their removal lowered composite scores in the simulation.
  4. After measure removal, ratings decreased for 35.1% of contracts, remained unchanged for 62.6%, and increased for 2.4%.
  5. The modeled annual 2026 quality bonus payment pool fell by $2.09 billion, or 13.9%, as 33 contracts lost eligibility and 6 gained it.
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Acr Open Rheumatology

  • October 23, 2026
Necrotizing Myositis as an Uncommon Initial Presentation of Childhood-Onset Granulomatosis With Polyangiitis: A Case Report
  • Rachel Guess
  • Bradley Ornstein
  • October 23, 2026

Objective: To describe an atypical initial presentation of childhood-onset granulomatosis with polyangiitis (GPA) involving suspected necrotizing myositis. Appr

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National Institutes Of Health

  • October 23, 2026
Precision T-cell treatment slows resistant cancers in early clinical trial results
  • October 23, 2026

Objective: Assess the safety, optimal dose, and preliminary antitumor activity of invikafusp alfa (invika) in patients with advanced cancers, many resistant to

...more
2 min