MDSpire - MDSpire Home
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

MDSpire News

  • August 25, 2026
FDA expands gastroesophageal cancer options
  • Kathryn Wighton
  • August 25, 2026
  • 2 min

Objective: To inform about the FDA approval of zanidatamab-hrii for treating HER2-positive gastroesophageal adenocarcinoma. Approach: Treatment Options: Zanidat

...more
1 min

MDSpire News

  • August 25, 2026
FDA approves first therapy for warm autoimmune hemolytic anemia
  • Kathryn Wighton
  • August 25, 2026
  • 3 min

Objective: To report the FDA approval of nipocalimab-aahu (IMAAVY) for the treatment of warm autoimmune hemolytic anemia (wAIHA). Approach: Approval Details: Ni

...more

MDSpire News

  • August 25, 2026
Cervical spinal cord stimulation and poststroke arm function
  • Andrea Surnit
  • August 25, 2026
  • 3 min
  1. A feasibility trial involving 7 patients with chronic poststroke hemiparesis showed a 32% increase in strength during cervical epidural stimulation.
  2. Participants experienced a 5.6-point improvement in Fugl-Meyer Assessment scores during stimulation, with no serious adverse events reported.
  3. Three of the 7 participants demonstrated improved hand and finger movement during stimulation, indicating varied responses based on neurological characteristics.
  4. Spasticity decreased in all participants during the 4-week study, with an average improvement of 6.6 Fugl-Meyer Assessment points post-stimulation.
  5. The study's limitations include a small sample size and lack of a control group, emphasizing the need for further research to confirm findings.
...more

MDSpire News

  • August 25, 2026
Volatility priors may reveal delusion severity in schizophrenia
  • Andrea Surnit
  • August 25, 2026
  • 4 min

Objective: To investigate the relationship between environmental volatility expectations and delusion severity in patients with schizophrenia-spectrum disorders

...more
2 min

Baptist Health South Florida

  • August 25, 2026
Jorge Bilbao, D.O., Joins Baptist Health Miami Neuroscience Institute as a Nonsurgical Spine Care Physician
  • August 25, 2026
  • 3 min

Objective: To introduce Dr. Jorge Bilbao and his role at Baptist Health Miami Neuroscience Institute. Approach: Clinical Focus: Dr. Bilbao specializes in physic

...more
1 min

MDSpire News

  • August 25, 2026
What shapes patient attitudes toward TBP skin cancer screening?
  • Andrea Surnit
  • August 25, 2026
  • 4 min

Objective: To identify factors influencing patients' experiences of total body photography (TBP) for skin cancer screening and diagnosis. Approach: Study Design

...more
2 min

MDSpire News

  • August 25, 2026
Outreach screening may uncover hearing loss
  • Andrea Surnit
  • August 25, 2026
  • 5 min

Objective: To evaluate the effectiveness of an outreach hearing program in identifying and managing hearing loss among patients with intellectual disability. Ap

...more
2 min

MDSpire News

  • August 25, 2026
Infant infections tied to later obesity
  • Doug Brunk
  • August 25, 2026
  • 4 min
  1. Infants with infections requiring medical care gained more weight and had higher obesity odds at ages 4 to 6 and 10 to 15, according to a Southern California study.
  2. The study analyzed data from 66,870 children aged 4 to 6 and 46,599 children aged 10 to 15, excluding those born prematurely or with low birth weight.
  3. Obesity was defined as a body mass index above the 95th percentile for age and sex, with rates increasing from 20% in uninfected children to 27% in treated infection cases.
  4. Children with untreated infections had 9% higher odds of obesity at ages 4 to 6 and 11% higher at ages 10 to 15 compared to those without infections.
  5. The study suggests that early infections may account for 2.4% to 10% of obesity in the population, but it does not establish causation or recommend treatment changes.
...more

Inside Dentistry

  • August 25, 2026
Annie Expands AI Platform with Dental Front Office Capabilities
  • News Staff
  • August 25, 2026
  • 2 min
  1. Annie has enhanced its AI platform for dental practices with new features for insurance verification, recare, appointment confirmation, and cancellation management.
  2. The platform functions as a 'digital coworker' to handle repetitive administrative tasks, building on existing AI receptionist capabilities.
  3. Annie can monitor patients for recare, initiate outreach when they are overdue, and contact those who completed hygiene appointments without scheduling next visits.
  4. The system manages appointment confirmations through texts and calls, allowing patients to reschedule or modify appointments seamlessly.
  5. Annie's new insurance verification features identify patients needing coverage checks and perform these tasks before appointments, integrating with practice management systems.
...more

The Pathologist

  • August 25, 2026
How Pathology Changed Medicine Forever
  • Jessica Allerton
  • August 25, 2026
  • 4 min
  1. Pathology has evolved from postmortem examinations to a technologically advanced field central to clinical decision-making.
  2. Histopathology advancements in the late 19th and early 20th centuries transformed pathology into a systematic science with standardized protocols.
  3. Molecular diagnostics and immunohistochemistry have shifted pathology's focus from disease appearance to understanding underlying biology.
  4. Digital pathology and artificial intelligence are enhancing diagnostic accuracy and efficiency, supporting pathologists rather than replacing them.
  5. Modern pathology integrates various analyses to provide comprehensive disease understanding, reinforcing its role in patient care.
...more

The Pathologist

  • August 25, 2026
The Missing Pieces of the Marmoset Genome
  • August 25, 2026
  • 3 min

Objective: To assemble a complete common marmoset genome and resolve previously missing or incorrectly represented regions. Approach: Genome Assembly: Researche

...more

The Ophthalmologist

  • August 25, 2026
Smart Lens, Sharp Signal
  • August 25, 2026
  • 3 min

Objective: To develop a smart contact lens for non-invasive ocular blood oxygen saturation monitoring. Approach: Device Design: A flexible plasmonic nano-confin

...more

The Ophthalmologist

  • August 25, 2026
Calculating the Myopic Nerve
  • August 25, 2026
  • 3 min

Objective: To estimate the probability of high myopia-associated glaucomatous or glaucoma-like optic neuropathy (GLON) and non-glaucomatous optic neuropathy (NG

...more

The Analytical Scientist

  • August 25, 2026
A Longer Life for Wildfire Smoke
  • August 25, 2026
  • 3 min
  1. Wildfire smoke and urban haze may persist longer in the atmosphere than current models predict due to slower evaporation of organic aerosol molecules.
  2. Researchers analyzed over 1,500 chemical species across 33 organic aerosol mixtures to study aerosol behavior and volatility.
  3. Apparent volatility in complex mixtures was reduced significantly, indicating that surrounding molecules stabilize compounds in the particle phase.
  4. Machine learning was used to compare molecular descriptors, showing that mixture-averaged properties better predict apparent volatility.
  5. Incorporating reduced volatility into atmospheric simulations suggested that smoke-derived organic aerosols may remain airborne longer than previously estimated.
...more

The Medicine Maker

  • August 25, 2026
Data Quality: Drug Discovery AI’s Indispensable Foundation
  • Andrea Jacobs
  • August 25, 2026
  • 6 min
  1. Pharmaceutical companies are increasingly investing in AI, as evidenced by partnerships like Novo Nordisk with OpenAI and Merck with Google Cloud.
  2. The quality of data used in AI models is crucial for reliable outputs in drug discovery, as messy data can lead to incorrect conclusions.
  3. Curated datasets improve AI prediction accuracy, as demonstrated by Isomorphic Labs, which achieved better results with a curated data infrastructure.
  4. Efficient AI in drug discovery leads to fewer false leads, quicker validation, and more confident decision-making when the data foundation is strong.
  5. The success of AI in drug discovery depends on the curation and structuring of data, rather than solely on the power of the AI models themselves.
...more

Frontiers In Neurology

  • August 25, 2026
Effects of Manual Acupuncture on Upper-Limb Motor Impairment Following Ischemic Stroke: Results from a Three-Group Randomized Controlled Study
  • Yu Min
  • Zhendong Huang
  • Ju Sun
  • Zetong Peng
  • Hongli Guan
  • Yuying Gong
  • Kaifeng Guo
  • August 25, 2026
  1. This study evaluated the effects of manual acupuncture combined with conventional rehabilitation on upper-limb motor dysfunction post-ischemic stroke.
  2. Manual acupuncture significantly improved FMA-UE scores compared to conventional rehabilitation and sham acupuncture, with differences of 9.64 and 8.57 points, respectively.
  3. Improvements in MBI scores were also greater with manual acupuncture, showing a difference of 7.32 points versus conventional rehabilitation.
  4. Functional near-infrared spectroscopy indicated greater activation in the ipsilesional prefrontal cortex and primary motor cortex with manual acupuncture.
  5. Three mild subcutaneous bleeding events were reported, but no serious adverse events occurred during the study.
...more

Frontiers In Neurology

  • August 25, 2026
Clinical Spectrum and Diagnostic Categorization of Neurosyphilis in Hospitalized Neurology Patients: A 16-Year Retrospective Analysis of Seropositivity
  • Duygu Özkan Yaşargün
  • August 25, 2026
  1. This study analyzed syphilis seropositivity in hospitalized neurology patients over a 16-year period.
  2. Out of 9,172 patients tested, 25 were included, with 10 classified as confirmed neurosyphilis and 5 as probable.
  3. MRI findings and positive neurological examinations at discharge significantly differed among diagnostic categories.
  4. No significant differences were found in age, sex, vascular ischemia, HIV status, or vascular involvement on CT.
  5. The study emphasizes the need for comprehensive diagnostic assessments for neurosyphilis beyond seropositivity.
...more

Frontiers In Oncology

  • August 25, 2026
Financial Impact of Cancer Treatment on Privately Insured Individuals in Lebanon: A Seven-Year Retrospective Cohort Study (2018–2024)
  • Shadi Saleh
  • Paul Makhoul
  • Rawad Chamandi
  • Zahi Abdul-Sater
  • August 25, 2026
  1. A retrospective cohort study analyzed cancer treatment costs for privately insured individuals in Lebanon from 2018 to 2024.
  2. The study included 16,617 unique cancer patients, generating 157,550 claims and a total expenditure of USD 239.9 million.
  3. Breast cancer was the most common diagnosis, accounting for 19.7% of cases, with surgery being the most utilized treatment modality.
  4. Annual cancer treatment spending increased from USD 35.7 million in 2018 to USD 48.9 million in 2024, despite a temporary decrease in 2022.
  5. The high-cost cohort, comprising 1.7% of patients, generated 23.0% of total spending, with lung cancer being the most prevalent in this group.
...more