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Frontiers In Neurology

  • August 12, 2026
Editorial: Volume II on Neurological and Neuropsychiatric Conditions in Military Personnel and Veterans
  • Lisa C. Krishnamurthy
  • Venkatagiri Krishnamurthy
  • Mary Jo Pugh
  • William C. Walker
  • Chen Lin
  • August 12, 2026
  1. Neurological and neuropsychiatric disorders are common among military personnel and Veterans, influenced by unique military service challenges.
  2. Conditions like TBI, PTSD, and chronic pain often manifest as interconnected syndromes, complicating diagnosis and treatment.
  3. Long-term monitoring and rehabilitation strategies are essential for Veterans, as neurological risks evolve significantly over time.
  4. Recognition of symptoms is crucial for effective care, as many may be misattributed to other disorders, hindering appropriate intervention.
  5. The health burden extends beyond individuals to families, with psychological distress affecting caregivers differently based on their roles.
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Frontiers In Immunology

  • August 12, 2026
Analysis of Bibliometric Trends and Visual Insights on Macrophages in Traditional Chinese Medicine from 2003 to 2023
  • Ge Zhu
  • Mingjie Xu
  • Jingxing Li
  • Jiachun Xu
  • Zhen Zhou
  • August 12, 2026

Objective: To systematically analyze bibliometric trends in macrophage research within Traditional Chinese Medicine (TCM) from 2003 to 2023. Approach: Data Sour

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Frontiers In Surgery

  • August 12, 2026
Navigating Diagnostic Difficulties in Boerhaave Syndrome with Bilateral Pleural Involvement: The Complementary Functions of CT Imaging, Endoscopy, and Video-Assisted Thoracoscopic Surgery
  • Junxue Han
  • Ximing Mu
  • Chaojie Xue
  • Aofei Yang
  • Shujuan Bai
  • Dongde Li
  • August 12, 2026
  1. Boerhaave syndrome is a rare condition caused by esophageal perforation, often following severe vomiting, leading to serious complications.
  2. Diagnosis can be challenging, as imaging may not always localize the perforation, complicating timely treatment.
  3. A 36-year-old male patient presented with chest pain after vomiting, with CT revealing bilateral pleural effusions and pneumomediastinum.
  4. The patient underwent video-assisted thoracoscopic surgery, which included pleural debridement and drainage, leading to recovery.
  5. Effective diagnosis and management of Boerhaave syndrome require a multidisciplinary approach involving various specialists.
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Frontiers In Surgery

  • August 12, 2026
A Case Study of De Garengeot Hernia Complicated by Intestinal Obstruction and Appendiceal Abscess in an Elderly Patient from Peru
  • Alvaro Veleto
  • Cesar Sapaico-Del-Castillo
  • Roberto Orta-Barriga
  • Mijail Vega-Barriga
  • Carla Cuya-Zevallos
  • August 12, 2026
  1. The De Garengeot hernia involves the vermiform appendix within a femoral hernia sac, occurring in 0.5–5% of femoral hernia cases.
  2. Acute appendicitis within a De Garengeot hernia is rare, with an incidence of 0.08–0.13%, complicating preoperative diagnosis.
  3. An 86-year-old woman presented with colicky abdominal pain, nausea, vomiting, and signs of dehydration after a recent inguinal abscess drainage.
  4. Exploratory laparotomy revealed acute appendicitis with an appendiceal abscess, complicated by a De Garengeot hernia and intestinal obstruction.
  5. Postoperative treatment included intravenous antibiotics, and the patient was discharged on day ten without complications.
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Frontiers In Immunology

  • August 12, 2026
Genetic Profiling of HIV-1 Proviruses in Immunological Non-Responders Under Antiretroviral Therapy
  • Shengquan Tang
  • Yue Wang
  • Yanqiu Lu
  • Zhen Tong
  • Jiahui Guo
  • Yizhi Cui
  • Vijay Harypursat
  • Yemiao Chen
  • Jing Ouyang
  • Huan Li
  • Tong Wang
  • Quanhua Zhou
  • Yaokai Chen
  • August 12, 2026
  1. The study investigates the genetic characteristics of HIV-1 proviruses in immunological non-responders (INRs) and responders (IRs) on antiretroviral therapy.
  2. INRs exhibited higher levels of intact proviral genomes compared to IRs, indicating a distinct proviral landscape despite similar levels of defective proviruses.
  3. Defective proviruses comprised the majority of the reservoir in both INRs and IRs, with defects primarily located in the 3′ half of the genome.
  4. The research utilized near-full-length HIV-1 DNA amplification and third-generation sequencing to analyze proviral genomes in peripheral blood mononuclear cells.
  5. Findings suggest that the intact proviral reservoir may play a role in the insufficient immune reconstitution observed in INRs.
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Frontiers In Oncology

  • August 12, 2026
Case Study: A Diagnostic Challenge Involving Metachronous Pancreatic Metastasis from High-Grade Serous Ovarian Carcinoma
  • Bahaaeldin Baraka
  • Maryam Al-Ani
  • Adam Afife
  • Irshad Soomro
  • Srinivasan Madhusudan
  • August 12, 2026
  1. Ovarian cancer is a leading cause of mortality among gynecological cancers, with rare instances of metastasis to the pancreas.
  2. A systematic literature search identified 8 cases of pancreatic metastases from ovarian cancer, primarily high-grade serous carcinomas.
  3. Treatment for pancreatic metastases included surgical excision and chemotherapy, with outcomes assessed through radiological and histological evaluations.
  4. The case study describes a 69-year-old woman diagnosed with high-grade papillary serous adenocarcinoma who later developed pancreatic metastasis.
  5. Histopathological confirmation of pancreatic metastasis was achieved through an endoscopic ultrasound-guided biopsy in April 2023.
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Frontiers In Oncology

  • August 12, 2026
A Case Report of a Collision Tumor Featuring Poorly Differentiated Thyroid Carcinoma and Intrathyroid Thymic Carcinoma Associated with a Branchial Cleft-like Cyst
  • Sayed Ali Almahari
  • Jehad Hammad
  • Khalid Khan
  • Haneen Alboosta
  • Worood Husain
  • Jawaher Alansari
  • Yusuf Barhoom
  • August 12, 2026
  1. A collision tumor featuring poorly differentiated thyroid carcinoma (PDTC) and intrathyroid thymic carcinoma (ITTC) was reported in a 59-year-old male.
  2. The patient initially presented with a benign branchial cleft cyst, which later progressed to a poorly differentiated carcinoma with squamous differentiation.
  3. Histopathological analysis revealed distinct malignant components: PDTC and a squamous carcinoma associated with a benign cyst.
  4. Immunohistochemical profiling supported the diagnosis, showing PDTC markers and squamous component positivity for CK5/6 and p63.
  5. The patient succumbed to severe bronchopneumonia before further staging and treatment could be completed.
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Frontiers In Cardiovascular Medicine

  • August 12, 2026
Impact of Permanent Pacemaker Treatment on Growth Outcomes in Pediatric Patients with Complete Heart Block
  • Kutay Sel
  • Yasemin Nuran Dönmez
  • Hayrettin Hakan Aykan
  • Aydın Adıgüzel
  • İlker Ertuğrul
  • Tevfik Karagöz
  • August 12, 2026

Objective: To evaluate how permanent pacemaker (PM) implantation affects growth in children diagnosed with complete heart block (CHB). Approach: Study Design: E

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Frontiers In Surgery

  • August 12, 2026
Comparative Analysis of Performance Outcomes in a Virtual Gastroscopy Course Among Male and Female Endoscopists
  • Nathalie Young
  • Peter Elbe
  • Charlotte Höög
  • Ninos Oussi
  • Fredrik Swahn
  • Magnus Kjellman
  • Gabriel Sandblom
  • Lars Enochsson
  • August 12, 2026

Objective: To assess improvements in technical skills in a simulated setting, examine performance disparities based on gender among surgical and gastroenterolog

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Frontiers In Surgery

  • August 12, 2026
Approach to Iatrogenic Rectal Injuries After Radical Prostatectomy: Insights from a Decade of Experience in a Regional Australian Hospital and a Proposed Management Algorithm
  • Khang Duy Ricky Le
  • Kevin Kah Wai Yoong
  • Leon Yeung
  • Iman Hameed
  • Nicholas Ang
  • David Patrick Heath
  • David Lloyd
  • Minh Hung Nguyen
  • August 12, 2026
  1. Iatrogenic rectal injuries post-radical prostatectomy can lead to significant morbidity, including sepsis and fistulas.
  2. The study analyzed eight patients with rectal injuries, with three identified during surgery and five postoperatively.
  3. Management strategies varied based on injury timing, defect characteristics, and tissue quality, with successful outcomes reported.
  4. Three patients developed fistulas requiring complex reconstruction, while all patients healed without mortality.
  5. A proposed management algorithm aims to assist multidisciplinary teams in addressing rectal injuries in regional healthcare settings.
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Frontiers In Medicine

  • August 12, 2026
Cryobiopsy in Early Fibrosis: Enhancing Diagnosis and Treatment Opportunities
  • Claudia Carducci
  • Naftali Kaminski
  • Aurélien Justet
  • Sara Tomassetti
  • August 12, 2026
  1. Transbronchial lung cryobiopsy (TBLC) is a less invasive alternative to surgical lung biopsy for assessing interstitial lung diseases.
  2. The role of TBLC in diagnosing interstitial lung abnormalities and early interstitial lung diseases is not yet clearly defined.
  3. Standardized protocols for TBLC are lacking, affecting diagnostic performance and introducing variability across different centers.
  4. Cryobiopsy specimens provide sufficient alveolated tissue to identify histopathological patterns not detectable with traditional biopsies.
  5. There is a need for rigorously designed prospective studies to evaluate TBLC's potential in converting incidental findings into therapeutic opportunities.
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Frontiers In Immunology

  • August 12, 2026
Discovery and validation of essential oxidative phosphorylation-associated genes as indicators for immune response and diagnostic purposes in burn injuries
  • Jiaqi Xu
  • Yujie Cui
  • Kangdi Li
  • Jia Jia
  • Xinfeng Huang
  • August 12, 2026
  1. The study identified 23 differentially expressed oxidative phosphorylation-related genes in burn patients.
  2. Three core genes, ATP6V1C1, ECHS1, and LDHA, were significantly associated with burn progression and immune response.
  3. Distinct immune cell compositions were observed in burn patients, indicating varied immune activity between patient cohorts.
  4. In vitro experiments showed that knockdown of ATP6V1C1 or LDHA reduced pro-inflammatory cytokine secretion.
  5. A diagnostic nomogram based on the core genes demonstrated strong diagnostic capability for burn injuries.
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The Analytical Scientist

  • August 12, 2026
Mass Spec Roundup: Molecular Glues, Microbiomes, and Metabolomes
  • August 12, 2026
  • 6 min
  1. A multiplexed mass spectrometry screen identified DCAF11 as a molecular glue requiring glutathionylation for DDX18 degradation.
  2. The platform immobilizes E3 ligases on beads to enhance the discovery of molecular glues and their interactions with cellular proteins.
  3. In-source freezing improved IR-MALDESI spatial resolution and suppressed metabolic changes in fresh leaf tissue during mass spectrometry imaging.
  4. A five-way benchmark identified DIA- and Slice-PASEF as the best performers for gut metaproteomics, enhancing protein detection and functional coverage.
  5. DIA-based approaches generally recovered more proteins than DDA-PASEF, supporting better taxonomic and functional assignments in metaproteomics.
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Inside Dentistry

  • August 11, 2026
Registration Opens for 2026 Dental Testing & Regulatory Summit
  • News Staff
  • August 11, 2026
  • 3 min

Objective: To announce the opening of registration for the 2026 Dental Testing & Regulatory Summit and Educators Conference. Approach: Event Details: The summit

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Inside Dentistry

  • August 11, 2026
Ultradent Introduces Gemini Nova Cordless Diode Laser
  • News Staff
  • August 11, 2026
  • 2 min
  1. Ultradent Products, Inc. has launched the Gemini Nova™ cordless diode laser for soft-tissue procedures in dental practices.
  2. The Gemini Nova laser features a cordless handpiece, base, and foot pedal connected via Bluetooth for enhanced mobility.
  3. This device operates at dual wavelengths of 810 nm and 980 nm, offering three wavelength modes for dental applications.
  4. The Gemini Nova delivers 20 watts of peak, super-pulsed power for faster cutting and clean incisions in soft tissue.
  5. A 5.5-inch high-resolution touchscreen provides access to preset procedures and built-in protocols for various dental applications.
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MDSpire News

  • August 11, 2026
Adding CRP to CAD-guided TB screening offers no benefit
  • Julie Greenbaum
  • August 11, 2026
  • 6 min

Objective: To compare the effectiveness and cost-effectiveness of a CAD-only tuberculosis screening strategy versus a CAD-plus-CRP strategy. Approach: Study Des

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MDSpire News

  • August 11, 2026
PROM Thresholds May Clarify Hip Arthroscopy Outcomes
  • Andrea Surnit
  • August 11, 2026
  • 4 min
  1. The systematic review identified clinically meaningful thresholds for patient-reported outcome measures after hip arthroscopy for femoroacetabular impingement.
  2. Twenty-one studies involving 5,687 patients were included, with a low to moderate overall risk of bias.
  3. The modified Harris Hip Score had an average minimal clinically important difference of 14.6 and a patient-acceptable symptom state of 70.7.
  4. Variability in threshold values was noted due to different calculation methods used across studies, impacting interpretation.
  5. The authors cautioned against applying these thresholds universally, emphasizing the need for context-specific interpretation.
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MDSpire News

  • August 11, 2026
CHEST Issues OSA Guidance for Pregnancy
  • Kathryn Wighton
  • August 11, 2026
  • 4 min

Objective: To provide clinical practice guidelines on the management of obstructive sleep apnea (OSA) during pregnancy. Approach: Systematic Review: The CHEST p

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