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March 31, 2026

Meat Intake, APOE Status Linked to Cognitive Aging

Kathryn Wighton
March 31, 2026
4 min

A cohort study published in JAMA Network Open found that higher total meat consumption is linked to favorable cognitive outcomes among older individuals with sp

...more

Higher meat consumption linked to slower cognitive decline in select APOE genotypes.
No significant correlation found in other genotypes.
Processed meat intake associated with higher dementia risk.
Study included over 2,000 patients over 15 years.
Gender and age influenced outcomes, especially in female patients.
Study adjusted for lifestyle, dietary quality, and comorbidities.
Higher unprocessed meat intake linked to reduced death rates in specific genotypes.
Limitations include self-reported data and potential confounding factors.

March 31, 2026

Q&A: Your student loan questions, answered

Mary Beth Versaci
March 31, 2026
6 min

During a January webinar hosted by the American Dental Association, experts discussed the One Big Beautiful Bill Act, addressing over 60 questions regarding its

...more

The One Big Beautiful Bill Act impacts student loans for dental students.
KeyBank offers free consultations for ADA members on loan options.
Important deadlines for repayment plans are approaching, specifically
Parent borrowing limits are changing, capping at $20,000 per year for one student.
Public Service Loan Forgiveness requires 120 qualified payments.
Interest capitalization may occur when switching repayment plans.
Moving from income-driven repayment plans to refinancing is possible but carries risks.

The ASCO Post

March 31, 2026

Molecular Test Doubles Detection of Bile Duct Cancer

The ASCO Post Staff
March 31, 2026
3 min

A recent study led by Dr. Adam Slivka from the University of Pittsburgh introduces BiliSeq, a molecular test for diagnosing bile duct cancer more effectively th

...more

BiliSeq significantly improves bile duct cancer detection.
Sensitivity of BiliSeq is around 82%.
It is not a general screening test but targets specific patient groups.
The test provides treatment-relevant genetic information.
It holds promise for reducing unnecessary repeat testing.
Study included over 2,000 patients in the US.
Collaboration with institutions enhances the study's applicability.

The ASCO Post

March 31, 2026

‘Prostate Screening Saved My Life’—Is That Really True in Most Cases?

Derek Raghavan
March 31, 2026
7 min

Derek Raghavan, MD, PhD, discusses the contentious issue of prostate-specific antigen (PSA) screening for prostate cancer, highlighted by a recent TV advertisem

...more

PSA screening remains controversial in prostate cancer management.
Critics question the demonstrated survival benefits.
PSA correlates with prostate disease but may misrepresent cancer extent.
Experts suggest a balanced approach to screening policies.
Increased communication and rational strategy is needed in clinical practice.

The ASCO Post

March 31, 2026

Adjuvant Pembrolizumab Plus Belzutifan in Patients With RCC at Increased Risk of Recurrence

Jo Cavallo
March 31, 2026
4 min

The phase III LITESPARK-022 study investigated the combination of adjuvant pembrolizumab and belzutifan in patients with clear cell renal cell carcinoma at incr

...more

LITESPARK-022 study evaluated adjuvant pembrolizumab plus belzutifan.
Significant improvement in disease-free survival noted.
24-month survival rate: 80.7% for combination vs 73.7% for pembrolizumab alone.
Safety profile consistent with known drug profiles.
Longer-term follow-up needed for overall survival analysis.

March 31, 2026

FDA Monthly Preview: Key April Decisions to Watch

Kathryn Wighton
March 31, 2026
3 min

Upcoming FDA decisions in April could lead to significant advancements across various specialties, including neurology, nephrology, endocrinology, and infectiou

...more

FDA decisions expected in April across multiple specialties.
GTx-104 targets aneurysmal subarachnoid hemorrhage.
AXS-05 aims to treat Alzheimer's agitation.
Sparsentan is for focal segmental glomerulosclerosis.
Teplizumab seeks to delay type 1 diabetes progression.
DOR/ISL is an investigational treatment for HIV-
Various PDUFA target action dates throughout April.

Baptist Health South Florida

March 31, 2026

How FIU and Baptist Health are Using AI and Sound to Detect Heart Disease Earlier

March 31, 2026
5 min

Researchers from Florida International University (FIU) and Baptist Health South Florida are integrating artificial intelligence (AI) with digital stethoscopes

...more

Researchers are integrating AI with digital stethoscopes for heart disease detection.
Early signs of heart disease can now be detected more accurately.
AI achieved 95% accuracy for healthy sounds, 85% for diseased sounds.
Collaboration focuses on transitioning technology to clinical use.
Future vision includes home monitoring for patients.
The technology aims to enhance, not replace, physician assessments.
Large data sets will improve algorithm efficacy.

Baptist Health South Florida

March 31, 2026

Advancing Precision Oncology: What Pooled Trial Data Reveal About 177 Lu-PSMA-617 in mCRPC

March 31, 2026
3 min

Radiopharmaceutical therapy with 177Lu-PSMA-617 is transforming advanced prostate cancer treatment. During the 2026 ASTRO Radiopharmaceutical Symposium, investi

...more

177Lu-PSMA-617 targets advanced prostate cancer.
Pooled analysis from seven trials with >2,500 patients.
36% reduction in disease progression risk.
Inconsistent overall survival results due to trial variability.
Emphasis on need for multidisciplinary care in therapy delivery.
Strengthened confidence in treatment's reproducibility across patient populations.

March 31, 2026

Equal Pay in Ophthalmology? Not Yet

Kerri Miller
March 31, 2026
5 min

In 2024, female academic ophthalmologists earned only 85 to 91 cents for every dollar earned by their male counterparts, according to a study published in JAMA

...more

Women academic ophthalmologists earned 85-91 cents per male dollar in
Median total compensation increased from 2016 to 2024 but showed disparities by rank.
Average career earnings gap over 30 years for women is $1.04 million.
Growth in women's compensation is slower at higher ranks like professors and chairs.
Calls for compensation reform include equity in starting salaries and financial literacy education.

March 31, 2026

AHA Updates Heart-Healthy Dietary Guidance

Kerri Miller
March 31, 2026
7 min

The American Heart Association's 2026 dietary guidance prioritizes cardiovascular health through nine key dietary features, moving away from nutrient-level targ

...more

AHA's new dietary guidance focuses on nine heart-healthy dietary features.
Target population begins at 1 year of age.
Key components include whole grains, healthy fats, and reducing ultraprocessed foods.
CVD risk is linked to diet quality, not just specific nutrients.
Physical activity recommendations state at least 150 minutes per week for adults.
Emphasis on legumes and nuts as protein sources for heart health.
New alcohol consumption guidance discourages initiation for health benefits.

March 31, 2026

Sudden Death Trajectories in HFpEF, HFmrEF

Kathryn Wighton
March 31, 2026
4 min

A recent study analyzed the functional and health status changes in heart failure patients with preserved or mildly reduced ejection fraction prior to sudden de

...more

Sudden death represents 25-30% of deaths in heart failure with preserved ejection fraction.
Study followed 6,001 patients with a median of 2.7 years.
Patients showed modest worsening of functional status before sudden death.
NYHA class and natriuretic peptide levels were key measures.
Current guidelines do not recommend ICDs for primary prevention.
Findings highlight non-specific pre-death changes, complicating risk assessment.
Study sponsored by Bayer AG, with disclosures from researchers reported.

The Analytical Scientist

March 31, 2026

Mapping Lipid Rewiring During Drug-Induced Cell Death

March 31, 2026
2 min

Researchers from China have developed a mass spectrometry imaging (MSI) platform that provides unprecedented visualization of lipid metabolism at the single-cel

...more

Developed an MSI platform for single-cell lipid metabolism imaging.
Achieves ~800 nm spatial resolution.
Combines MSI with microscopy and LC-MS.
Analyzed HeLa and HepG2 cells under anticancer agents.
Observed distinct lipid fingerprints during apoptosis.
Shows potential in drug development and precision medicine.
Platform successfully imaged lipid distributions in mouse brain tissue.

The Analytical Scientist

March 31, 2026

Suspended Waveguide Chip Sniffs Gases at Parts-per-Billion Levels

March 31, 2026
1 min

The innovative photonic chip leverages an air-based waveguide to enhance gas detection sensitivity, achieving parts-per-billion accuracy and setting a new stand

...more

Photonic chip utilizes air for waveguide to enhance gas detection.
Achieves sensitivity to parts-per-billion levels.
45-fold increase in sensing efficiency over traditional sensors.
Detects acetylene at 330 ppb with fast results.
Operates in near-infrared spectrum for compatibility with telecom.
Potential for diverse applications in environmental and health monitoring.
Device compact, measuring only 1.2 cm long.

The Analytical Scientist

March 31, 2026

A Clearer Picture of Microplastics Hiding in Biosolids

James Strachan
March 31, 2026
3 min

Research conducted by a team from Lund University has demonstrated improved methods for detecting microplastics in biosolids, treated sewage sludge that is an e

...more

Study focuses on microplastics in biosolids from Swedish wastewater treatment.
O-PTIR spectroscopy used for particle identification.
Conventional methods often miss smaller microplastics.
Fenton oxidation plus cellulase digestion enhances sample purity.
New methods significantly reduce analysis time.
O-PTIR provides better quality spectra for small particles.
Method demonstrates significant improvements over FTIR and Raman techniques.

The Pathologist

March 31, 2026

It's Like PCR, But Better

Helen Bristow
March 31, 2026
2 min

mcPCR, showcased at AGBT 2026, revolutionizes molecular pathology by enabling PCR for methylation analysis. Traditional PCR fails to capture crucial methylation

...more

mcPCR enhances PCR capabilities for methylation analysis.
Traditional PCR misses crucial methylation patterns.
mcPCR combines primer extension with methyltransferase for accurate amplification.
It addresses challenges in high-throughput and low-input workflows.
mcPCR could lead to earlier detection and better monitoring of diseases.
Benefits include less invasive procedures and personalized therapy.
It broadens the use of methylation biomarkers in diagnostics.

The Pathologist

March 31, 2026

ctDNA Test Guides Breast Care in Elderly

March 31, 2026
2 min

A prospective study published in Clinical Cancer Research reveals that circulating tumor DNA (ctDNA) testing can help older women with estrogen receptor-positiv

...more

ctDNA can help identify eligibility for endocrine therapy in older women.
Study analyzed 43 patients aged 70 and older.
Persistent ctDNA indicates tumor progression after therapy.
Negative ctDNA suggests stability and low progression risk.
Testing can be done through routine blood draws from home.
ctDNA may personalize treatment and minimize invasive procedures.
Need for validation in larger trials before practice changes.
Immune-related features were found in progressing tumors.

The Ophthalmologist

March 31, 2026

"We Need Better Answers in Glaucoma"

March 31, 2026
5 min

Professor Gus Gazzard, recently recognized in the Ophthalmologist Power List, discusses the widening gap between therapeutic innovation in glaucoma and the capa

...more

Gaps exist in glaucoma treatment innovation and testing capabilities.
Collaboration among clinicians is vital for effective trial outcomes.
Registry-based trials can improve efficiency and patient involvement.
Fragility Indices and WIN ratios are emerging tools for trial robustness.
AI can enhance outcomes but is not essential for immediate improvements.

The Ophthalmologist

March 31, 2026

IOL Calculation Formulas: What Should the Ophthalmologist Expect？

Andrzej Grzybowski
Geng Wang
Danye Mei
March 31, 2026
5 min

Modern cataract surgery emphasizes the accurate preoperative calculation of intraocular lens (IOL) power, evolving through generations from linear regression to

...more

IOL power calculation is crucial for optimal cataract surgery outcomes.
Evolution from linear regression to AI-based formulas enhances accuracy.
Formula selection should be personalized based on axial length.
Short eyes benefit from Hoffer Q and AI-based formulas like PEARL-DGS.
Normal axial lengths have good outcomes with SRK/T and Barrett Universal II.
Long axial lengths require adjustments to prevent hyperopic shifts.
Ongoing research needed to establish stable IOL selection criteria.

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