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MDSpire News

  • November 12, 2026
Can PAP resume immediately after sinus surgery?
  • Andrea Surnit
  • November 12, 2026
  • 4 min

Objective: To assess whether resuming positive airway pressure (PAP) on postoperative day 0 or 1 is associated with sinonasal outcomes after functional endoscop

...more
2 min

MDSpire News

  • November 12, 2026
Can CTCA prevent cardiac event after MI ruled out?
  • Andrea Surnit
  • November 12, 2026
  • 4 min

Objective: To assess whether CT coronary angiography (CTCA)-guided care reduces subsequent myocardial infarction or cardiovascular death in patients with suspec

...more
2 min

MDSpire News

  • November 12, 2026
Physician identified as suspect in deadly DC shooting
  • Teraya Smith
  • November 12, 2026
  • 3 min

Objective: The article reports the November 12 shooting at and outside VIDA Fitness in Washington, DC, the police response, and condominium complaints described

...more
2 min

MDSpire News

  • November 12, 2026
USB-powered warm compresses improve tear stability
  • Andrea Surnit
  • November 12, 2026
  • 4 min

Objective: To compare short-term effects of a USB-powered warm compress and a disposable self-heating mask in adults with meibomian gland dysfunction. Approach:

...more
2 min

MDSpire News

  • November 12, 2026
Poor sleep may link extreme heat to suicide risk
  • Andrea Surnit
  • November 12, 2026
  • 6 min

Objective: To assess associations between heat exposure and suicide risk in Bangladesh and examine whether sleep quality or emotional dysregulation statisticall

...more
2 min

The Pathologist

  • November 12, 2026
Reading the Methylation Map
  • Helen Bristow
  • November 12, 2026
  • 8 min

Get a concise, at-a-glance scorecard that distills clinical guidelines into key recommendations, patient insights, and treatment considerations.

View Scorecard

The Medicine Maker

  • November 12, 2026
Can Better Biomarkers Reduce Drug Failure?
  • Andreas Wolf
  • November 12, 2026
  • 7 min
  1. Roughly 9 in 10 drugs entering clinical trials fail to reach the market, contributing to drug development costs.
  2. Single biomarkers and poorly defined trial populations can obscure treatment effects in subgroups that might respond.
  3. Biomarker constellations across biological layers, analyzed with tools such as AI and machine learning, may improve patient stratification.
  4. NMR spectroscopy can convert blood or urine biomarker data into digital data for repeated analysis without additional sample processing.
  5. Less invasive liquid biopsies and digital monitoring can provide more frequent assessments and may reduce travel burdens for trial participants.
...more

The Analytical Scientist

  • November 12, 2026
Raman Spectroscopy Takes On Maple Syrup Grading
  • November 12, 2026
  • 3 min

Objective: Assess whether Raman spectroscopy combined with machine learning can estimate multiple maple syrup quality attributes from one analytical workflow. A

...more
2 min

The Analytical Scientist

  • November 12, 2026
Tracking Tumor Cell Damage With Raman Spectroscopy
  • November 12, 2026
  • 3 min

Objective: To develop a method for mapping local pH changes in 3D breast cancer models after different forms of cellular stress. Approach: Sensor and model: Res

...more
2 min

MDSpire News

  • November 12, 2026
WHO 2026 global TB report: Mortality misses 2025 target
  • Teraya Smith
  • November 12, 2026
  • 3 min

Objective: The report summarizes global TB burden, diagnosis and treatment coverage, prevention, costs, and funding in 2025, and compares progress with WHO mile

...more
2 min

MDSpire News

  • November 12, 2026
Medical Oddities: A broken heart courtesy of the flu
  • Teraya Smith
  • November 12, 2026
  • 6 min

Objective: The article summarizes a case of Takotsubo cardiomyopathy following influenza A and research on frozen hair follicles, language in dreams and mind-wa

...more
2 min

Jama Network Open

  • November 12, 2026
Cefazolin Compared With Cloxacillin for MSSA Bacteremia: Meta-Analysis of Two Randomized Trials
  • Todd C. Lee
  • Steven Y. C. Tong
  • Joshua S. Davis
  • Arthur M. Albuquerque
  • Matthew P. Cheng
  • Jacob Dye
  • Nesrin Ghanem-Zoubi
  • Anna L. Goodman
  • Nynke G. L. Jager
  • Achim J. Kaasch
  • Ilse J. E. Kouijzer
  • David C. Lye
  • Alistair R. D. McLean
  • Brendan J. McMullan
  • David L. Paterson
  • Connor Prosty
  • Jason A. Roberts
  • Pierre Tattevin
  • Jonas Tverring
  • Dafna Yahav
  • Emily G. McDonald
  • November 12, 2026

Objective: To synthesize mortality and key safety outcomes from the CloCeBa and SNAP randomized trials comparing cefazolin with antistaphylococcal penicillins f

...more
2 min

Critical Care

  • November 12, 2026
Assessing NLRP3 Inflammasome Function in Sepsis: An Overlooked Element of Precision Medicine
  • Pablo Pelegrín
  • Ricard Ferrer
  • Carlos García-Palenciano
  • November 12, 2026

Objective: To distinguish measurements of inflammasome-associated biomarkers from assessments of immune cells’ functional capacity to activate the NLRP3 inflamm

...more
2 min

Jama Network Open

  • November 12, 2026
Association of Time to Surgery With Survival in Stage I Non–Small Cell Lung Cancer
  • Vikram Krishna
  • Claire Perez
  • Drew Bolster
  • Kellie Knabe
  • Raffaele Rocco
  • Philicia Moonsamy
  • Clark B. Fuller
  • Harmik J. Soukiasian
  • Andrew R. Brownlee
  • November 12, 2026

Objective: To assess the association between diagnosis-to-surgery interval and long-term survival among patients with stage I NSCLC undergoing anatomic resectio

...more
2 min

Bmc Medicine

  • November 12, 2026
Combined SPG7 and AFG3L2 Mutations Are Associated with Late-Onset Ataxia and Pyramidal Signs
  • Efthymia Kafantari
  • Sorina Gorcenco
  • Andreas Puschmann
  • November 12, 2026

Objective: To describe a patient with late-onset ataxia and heterozygous variants in SPG7 and AFG3L2, and relate the case to previously reported patients with t

...more
3 min

Intensive Care Medicine

  • November 12, 2026
A Dynamic Pulmonary-Systemic Framework for Understanding Progression from Pneumonia to ARDS
  • Ignacio Martin-Loeches
  • Ricard Ferrer
  • Pedro Póvoa
  • November 12, 2026

Get a concise, at-a-glance scorecard that distills clinical guidelines into key recommendations, patient insights, and treatment considerations.

View Scorecard

Jama Network Open

  • November 12, 2026
Cefazolin Compared With Antistaphylococcal Penicillins for Methicillin-Susceptible Staphylococcus aureus Infections
  • Michihiko Goto
  • November 12, 2026

Objective: The article examines the objective, findings, and clinical context described in Cefazolin Compared With Antistaphylococcal Penicillins for Methicilli

...more
3 min

Eye

  • November 12, 2026
Visual Difficulty and Voting Participation Among Adults in the United States
  • Megan M. Tran
  • John C. Lin
  • Patrick Akarapimand
  • Ali G. Hamedani
  • November 12, 2026

Objective: Assess the association between self-reported visual difficulty and civic engagement among U.S. adults. Approach: Design and data: Serial cross-sectio

...more
2 min