Helicobacter pylori infection is independently associated with triglyceride levels: a propensity score–matched cross-sectional study
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By
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March 25, 2026
Objective:
To investigate the association between H. pylori infection and serum lipid levels, specifically triglycerides.
Key Findings:
- H. pylori-positive participants had significantly higher triglyceride levels compared to H. pylori-negative participants, even after adjusting for confounding factors.
- No significant differences were found in total cholesterol, LDL-C, or HDL-C levels between the two groups.
Interpretation:
The findings suggest that H. pylori infection may play a role in dyslipidemia, particularly in elevating triglyceride levels, which could have implications for metabolic risk assessment. Further research is needed to establish causality.
Limitations:
- The study design is cross-sectional, limiting causal inference.
- The sample size may not be representative of the general population.
- Potential confounding factors not accounted for may influence lipid levels.
- The single-center design may introduce selection bias.
Conclusion:
H. pylori infection is associated with higher triglyceride levels, warranting further investigation into its role in metabolic health, particularly in diverse populations.
