From the Journals

Bladder Cancer Risk Markedly Elevated in MS

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A French study in Neurology analyzed data on 140,649 multiple sclerosis patients and 562,596 matched controls, finding a slightly elevated overall cancer risk in MS patients compared to the general population. The study revealed variations in cancer risk by type, age group, and sex, noting increased risks for bladder, brain/CNS, cervical, and kidney cancers, and decreased risks for prostate, breast, and colorectal cancers. MS patients exhibited lower participation rates in national cancer screening programs, especially in older age groups. Utilizing a large sample size and nationwide data, the study's strengths include a long follow-up period, while limitations include potential surveillance bias and the inability to adjust for lifestyle factors or MS clinical characteristics.

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