Bladder Cancer Risk Markedly Elevated in MS
A nationwide French study of over 140,000 multiple sclerosis patients found a 71% increased risk of bladder cancer compared to the general population, with an even more pronounced risk in women with MS.
A French study in Neurology analyzed data on 140,649 multiple sclerosis patients and 562,596 matched controls, finding a slightly elevated overall cancer risk in MS patients compared to the general population. The study revealed variations in cancer risk by type, age group, and sex, noting increased risks for bladder, brain/CNS, cervical, and kidney cancers, and decreased risks for prostate, breast, and colorectal cancers. MS patients exhibited lower participation rates in national cancer screening programs, especially in older age groups. Utilizing a large sample size and nationwide data, the study's strengths include a long follow-up period, while limitations include potential surveillance bias and the inability to adjust for lifestyle factors or MS clinical characteristics.
1. Study in Neurology found slightly elevated overall cancer risk in MS patients compared to the general population. 2. Variations in cancer risk observed by type, age group, and sex. 3. Bladder, brain/CNS, cervical, and kidney cancers showed increased risk, while prostate, breast, and colorectal cancers showed decreased risk in MS patients. 4. Lower participation rates in national cancer screening programs were noted for MS patients, especially in older age groups. 5. Utilized a large sample size and nationwide data. 6. Strengths include long follow-up period. 7. Limitations include potential surveillance bias and inability to adjust for lifestyle factors or MS clinical characteristics.