Putting a POC Troponin to the Test
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By
February 5, 2026
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3 min
A multicenter study confirmed the reliability of the QuidelOrtho TriageTrue high-sensitivity troponin I (hs-TnI) assay, demonstrating acceptable precision and minimal interference with analytical performance. The assessment involved 200 samples measuring concordance against laboratory assays. Results revealed intra-assay precision coefficients of variation (CV) between 2.8% and 15.9% at varying troponin levels, with correlations up to 0.99, indicating strong performance for myocardial infarction diagnosis in clinical settings. Further validation supports its integration into emergency protocols.
1. The study verified the hs-TnI assay's precision and analytical performance.2. Intra-assay CVs ranged from 2.8% to 15.9%.3. Hemolysis interference was minimal up to 10 g/L.4. Correlation coefficients with other assays were as high as 0.99.5. The assay performs adequately for diagnosing myocardial infarction in various settings.6. Limitations included logistical constraints in sample collection.7. Recommendations support integration into emergency care pathways.
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