Spectroscopy’s Surprising LEGO Revolution  - Summary - MDSpire
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Spectroscopy’s Surprising LEGO Revolution 

A trilogy of studies uses LEGO “standards” to evaluate portable Raman performance – and the promise of SPAD-based Raman

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Richard Crocombe and colleagues have discovered that LEGO blocks serve as effective standard samples for overcoming fluorescence interference in Raman spectroscopy. Their research evaluates the impact of fluorescence on handheld Raman instruments, showing varying performance based on excitation wavelengths and mitigation strategies. Despite limitations with the current single photon avalanche photodiode (SPAD) technology, the team believes SPAD has future potential in forensic and environmental applications. Their findings suggest that no single excitation method is universally effective, necessitating adaptable instrument designs for real-world samples.

Original Source(s)

Spectroscopy’s Surprising LEGO Revolution 

  • by James Strachan

  • April 3, 2026

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