A study published in Nature Communications identified four significant topological turning points in human brain networks during lifespan, from birth to age 90, using advanced diffusion imaging data analysis. These turning points, occurring at ages 9, 32, 66, and 83, indicate distinct organizational epochs in brain topology characterized by varying integration and segregation dynamics. The research utilized data from 4,216 participants and revealed crucial insights into brain development, cognitive changes, and potential implications for understanding aging-related cognitive decline.
1. Key turning points: ages 9, 32, 66, 83. 2. Analysis using 12 graph theory metrics. 3. Integrated data from nine diffusion imaging datasets. 4. Epochs show unique topological characteristics. 5. Importance of age-related brain maturation and decline. 6. Cross-sectional design may limit individual trajectory insights. 7. Further longitudinal studies recommended.
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