From the Journals

Metformin and AMD: Signal or Noise?

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A study linked metformin use to a 37% lower incidence of intermediate age-related macular degeneration (AMD) over five years in type 2 diabetes patients. Conducted under the ISDR program in Liverpool, UK, this population-based research utilized systematic retinal image grading instead of administrative data, enhancing its reliability. Although baseline data showed varying AMD stages, metformin did not affect early AMD progression. Findings suggest metformin's potential benefits beyond glycemic control, warranting further clinical trials, despite observational limitations.

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