From the Journals

AI Meets Molecular Testing in Thyroid Nodules

This combined approach has the potential to improve patient outcomes ... without negatively impacting long-term cancer-related outcomes.”

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A recent retrospective study published in Endocrine Practice highlights the integration of an AI-based ultrasound model with molecular testing to enhance diagnostic accuracy in patients with indeterminate thyroid nodules. The study found that while maintaining a sensitivity of 95%, specificity and positive predictive value improved significantly when the two methods were combined. Conducted by researchers at the University of Nebraska Medical Center, the findings suggest potential advancements in precision medicine for thyroidology, though larger studies are needed for validation.

Original Source(s)

AI Meets Molecular Testing in Thyroid Nodules

This combined approach has the potential to improve patient outcomes ... without negatively impacting long-term cancer-related outcomes.”

  • by Julia Cipriano, MS, CMPP

  • February 26, 2026

  • 5 min

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