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Sequencing Therapies in Non-Hodgkin Lymphomas

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At JADPRO Live 2025, F. Brianne Buchanan, PA-C, and Tatjana Grgic, PharmD, provided insights on selecting and sequencing therapies for relapsed/refractory B-cell non-Hodgkin lymphomas. Emphasis was placed on Bruton tyrosine kinase (BTK) inhibitors, bispecific antibodies, and CAR T-cell therapies. Challenges include managing drug interactions, monitoring for toxicity like CRS and ICANS, and considering patient-specific factors. The talk highlighted logistical considerations and the importance of palliative care to enhance patients' quality of life throughout treatment.

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