From the Journals

Early Hip Fracture Surgery Safe in Patients on DOACs

Multicenter cohort findings indicate that early surgery in patients on direct oral anticoagulants was associated with shorter hospitalization without increased bleeding.

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A multicenter retrospective cohort study involving 875 patients aged 70 and older with hip fractures revealed that surgery within 24 hours for those on direct oral anticoagulants (DOACs) does not lead to a significantly greater perioperative hemoglobin decrease compared to delayed surgery. The primary analysis demonstrated a median hemoglobin decrease of 0.6 mmol/L in the early surgery group versus 0.9 mmol/L in the delayed group. Additionally, early surgery was correlated with shorter hospital stays and marginally lower mortality. Limitations includes data gaps regarding DOAC doses and patient comorbidities.

Original Source(s)

Early Hip Fracture Surgery Safe in Patients on DOACs

Multicenter cohort findings indicate that early surgery in patients on direct oral anticoagulants was associated with shorter hospitalization without increased bleeding.

  • by Julie Greenbaum

  • February 27, 2026

  • 4 min

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