Liver Supplements: Big Sales, Limited Evidence
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By
January 30, 2026
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3 min
A recent study analyzed the top 20 bestselling liver cleanse supplements on Amazon, revealing that while these products claimed to promote detoxification and enhance liver function, most lacked robust clinical evidence to support their assertions. The investigation found estimated annual sales exceeding $38.8 million, driven by consumer ratings and product age. Key ingredients such as milk thistle showed mixed clinical support, with negative reviews often citing inefficacy and gastrointestinal side effects. The findings highlight the need for increased scrutiny in the liver supplement market, particularly as sales continue to rise despite limited scientific backing.
1. Study analyzed 20 bestselling liver cleanse supplements on Amazon. 2. Estimated annual sales exceeded $38.8 million. 3. Claims of detoxification and liver enhancement were widespread. 4. Most ingredients lacked robust clinical support. 5. Milk thistle was found in 95% of products. 6. 62% of negative reviews cited inefficacy. 7. Research highlights need for scrutiny in the supplement market. 8. Methodology involved structured PubMed searches and review authenticity assessment.
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