Video: Reducing Injections in Wet AMD
Avni Finn, MD, and Diana V. Do, MD, discuss promising results from the DAVIO2 trial of EYP-1901.
Dr. Avni Finn presented key insights at the 2025 American Society of Retina Specialists Annual Meeting, revealing promising results from the DAVIO2 trial involving EYP-1901, a novel tyrosine kinase inhibitor designed to reduce the treatment burden for patients with wet macular degeneration. Traditionally, patients endure frequent anti-VEGF injections to maintain vision; however, the trial demonstrated that with EYP-1901, patients significantly reduced their injection frequency from an average of 10 to just 1 or 2 supplemental injections per year. This innovation could transform treatment practices, enhancing patient compliance and outcomes.
1. EYP-1901 is a tyrosine kinase inhibitor for wet macular degeneration.2. Patients traditionally need frequent anti-VEGF injections.3. DAVIO2 trial showed reduction of injections from 10 to 1-2 yearly.4. EYP-1901 offers a longer lasting treatment option (~6 months).5. Potential to lower treatment burden and improve compliance.