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Neurofilament Levels Linked to AF Risk

Higher levels associated with stroke, death, and heart failure in long-term cohort

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This study identifies a significant correlation between serum neurofilament light chain (NfL) levels and the risk of major vascular events and mortality among patients with atrial fibrillation (AF) throughout a median follow-up of 8 years. Findings reveal that each doubling of NfL levels increases the risk of cardiovascular death, nonfatal stroke, heart failure-related hospitalization, and all-cause mortality. Conducted within 14 Swiss centers, the observational study highlights NfL as a potentially valuable biomarker for evaluating cardiovascular risks in AF patients.

Original Source(s)

Neurofilament Levels Linked to AF Risk

  • by Andrea Surnit

  • March 30, 2026

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