Personalizing Steroid Duration in Asthma
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By
February 3, 2026
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3 min
A study conducted in Singapore evaluated the efficacy of using baseline blood eosinophil counts to guide systemic corticosteroid treatment duration in hospitalized asthma patients. The randomized trial involved 110 adults and found that tailoring corticosteroid length based on eosinophil levels achieved similar clinical outcomes while significantly reducing steroid exposure for noneosinophilic patients. The treatment strategy yielded only slightly higher treatment failure rates compared to standard care, with no severe complications noted, indicating a promising approach for managing asthma exacerbations.
1. Study evaluates eosinophil count-guided corticosteroid duration for asthma.2. Conducted in Singapore with 110 adult patients.3. Eosinophil-guided approach reduced steroid exposure.4. Treatment failure rate: 11% (eosinophil-guided) vs 7% (usual care).5. 60% patients had eosinophilic exacerbations.6. No severe complications observed in either group.7. Requires larger, diverse studies for confirmation.8. Findings published in Thorax by Anthony Yii and colleagues.
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