FDA & Government News

Flu Vaccine Cut Hospitalizations Despite Drifted H3N2 Strain

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The 2025–2026 seasonal influenza vaccine provided significant protection, reducing outpatient visits by 22% to 34% and hospitalizations by 30%, with higher efficacy observed in pediatric patients (38% to 41%). Data from over 142,000 patients highlighted notable effectiveness variations against different influenza strains, particularly for influenza B. The study adjusted for multiple confounders and found overall vaccine effectiveness consistent with international estimates. Despite some limitations in data, the authors emphasized the importance of vaccination and antiviral treatments in mitigating influenza morbidity.

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