New Vaccine Prevents Severe RSV Illness
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December 13, 2024
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2 min
A large-scale study conducted at Kaiser Permanente Southern California found that the respiratory syncytial virus prefusion F vaccine was 91% effective at preventing RSV-related hospitalizations and emergency department visits among adults aged 60 years and older. The retrospective case-control study analyzed data from 7,047 lower respiratory tract disease encounters, and the researchers found an adjusted vaccine effectiveness of 91%. Vaccinating approximately 250 persons could prevent one RSV-related emergency department visit or hospitalization in the first season after vaccination. The study represented the first major real-world effectiveness analysis of RSVpreF vaccination since its licensure in 2023.
1. RSV-preF vaccine was 91% effective at preventing RSV-related hospitalizations and emergency department visits in adults aged 60 years and older. 2. The study analyzed data from 7,047 lower respiratory tract disease encounters. 3. Vaccinating approximately 250 persons could prevent one RSV-related emergency department visit or hospitalization in the first season after vaccination. 4. 57.4% of participants were aged 75 or older. 5. The investigation employed salvaged respiratory specimens for enhanced testing methods, increasing the study size.
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