Short TTP Linked to Infective Endocarditis Risk
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By
February 9, 2026
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4 min
A population-based study involving 463 adults in southern Sweden investigated the relationship between time to blood culture positivity (TTP) and infective endocarditis (IE) in Streptococcus agalactiae bacteremia from 2016 to 2023. The median age of participants was 72, with 23 cases of IE identified. Results indicated a shorter TTP was linked to IE but not to mortality or sepsis. Significant limitations of the study included its retrospective design and potential biases, while the strengths involved a large cohort and detailed microbiological data, providing valuable insights into patient management.
1. Study evaluated 463 adults with S. agalactiae bacteremia. 2. Median patient age was 72 years, mostly male. 3. Shorter TTP associated with infective endocarditis but not mortality. 4. 30-day mortality rate was 9%. 5. Limitations: retrospective design, preanalytical delay impact. 6. Skin and soft tissue infections were common. 7. Study strengths included large cohort and microbiological data.
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