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From the Journals

When Guillain-Barré Signals Lyme 

  • March 25, 2026

  • 3 min

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A case study highlights a 61-year-old woman who developed Guillain-Barré syndrome linked to Lyme disease, emphasizing the complex diagnostic process when acute inflammatory neuropathy coincides with tick-borne infections. After two weeks of fatigue, she presented with acute lower limb weakness and abnormal neurological findings. Testing revealed features consistent with Guillain-Barré syndrome, leading to a diagnosis of Lyme disease after facial palsy developed. This case underscores the need for vigilance in diagnosing Lyme disease in atypical GBS presentations.

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