From the Journals

SABCS Highlights: Advances in Oral SERD's for Breast Cancer

  • March 17, 2026

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The lidERA, evERA, and EMBER-3 trials represent significant advances in the research of oral selective estrogen receptor degraders (SERDs), as discussed by Harold Burstein, MD, PhD, and Rinath M. Jeselsohn, MD. These trials aim to evaluate the effectiveness and safety of SERDs in treating hormone receptor-positive breast cancer. Such therapies have the potential to improve patient outcomes by targeting resistant cancer cells and offering new avenues for treatment, particularly for patients with advanced disease.

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