Can Social Factors Derail Bariatric Gains?
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By
January 20, 2026
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2 min
In a comprehensive analysis of the Alliance of Randomized Trials, researchers, led by Dr. Mary Elizabeth Patti from Joslin Diabetes Center, found that metabolic bariatric surgery outperforms medical therapy in improving glycemic control and achieving weight loss in type 2 diabetes patients. This study, encompassing 258 patients across four U.S. academic centers, examined the impact of social deprivation through the Area Deprivation Index (ADI) on outcomes. Although surgery proved superior for HbA1c reduction and weight loss, no significant differences based on ADI were detected.
1. Metabolic surgery shows better outcomes for diabetes than medical therapy.2. Study involved 258 patients and utilized randomized trials.3. Social deprivation assessed using Area Deprivation Index.4. Weight loss and HbA1c levels improved with surgery.5. Study limitations included small size and trial design.6. No significant difference in outcomes based on ADI.7. Findings aim to influence diabetes management strategies.
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