A nationwide cohort study from Taiwan indicates that children undergoing appendectomy may have a higher long-term risk of nontyphoidal Salmonella (NTS) infection. Analyzing data from nearly 18,700 pediatric patients who underwent appendectomy and matched controls, researchers found those who had the procedure were 1.58 times more likely to develop NTS. This risk was particularly significant in children under five. The appendix's role in gut immunity may explain this increased susceptibility, suggesting a need for preventive strategies post-appendectomy.
1. Appendectomy increases long-term NTS infection risk in children. 2. The study involved 18,654 appendectomy patients vs. 74,616 controls. 3. Children under 5 have nearly double the risk of NTS post-appendectomy. 4. Risk is elevated but varies across different age groups. 5. The appendix may serve a protective role in gut immunity. 6. Surveillance and preventive strategies may be needed for children post-appendectomy.
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