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CRISPR “Gene Drive” Reverses Antibiotic Resistance in Bacteria

Population-wide editing system strips resistance genes – even inside hard-to-treat biofilms

  • April 2, 2026

  • 2 min

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Researchers at the University of California San Diego have developed a CRISPR-based tool to combat antibiotic resistance by removing the genes responsible for it from bacterial populations. This innovative system, known as pPro-MobV, employs a conjugation-based transfer process that allows for efficient gene editing throughout bacterial communities, including challenging biofilms associated with chronic infections. With its versatile applications in clinical and environmental settings and a safeguard mechanism for gene removal, this technology could transform antibiotic treatment strategies.

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CRISPR “Gene Drive” Reverses Antibiotic Resistance in Bacteria

  • April 2, 2026

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