Bioelectronic Patch Intervenes to Manage Blood Pressure
November 27, 2025
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4 min
Researchers have developed a closed-loop bioelectronic patch aimed at improving hypertension management by delivering therapy in real-time. This system combines advanced microneedle technology and electrochemical methods to release nitric oxide when blood pressure spikes, offering a potential alternative to traditional oral medications, especially for patients with unstable blood pressure. Interdisciplinary collaboration played a crucial role in optimizing the technology, which may extend beyond hypertension to treat conditions such as arrhythmia and chronic wounds. Wansong Chen from Central South University led the research published in Science Advances.
1. Closed-loop patch delivers nitric oxide for blood pressure spikes. 2. Combines microneedle technology with electrochemical methods. 3. Targeted towards patients with unstable blood pressure. 4. Interdisciplinary collaboration was key in development. 5. Future exploration for other therapeutic targets is planned. 6. Testing in pig models shows potential for human trials. 7. Possible applications extend beyond hypertension to other conditions.
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