Nano-IR Spectroscopy Maps Molecules Inside Living Cells
November 6, 2025
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2 min
Researchers have developed a pioneering nano-infrared (nano-IR) spectroscopy technique to visualize the molecular composition of living animal cells in their natural liquid environment. This study, led by Alexander Veber from Helmholtz-Zentrum Berlin, marks a significant advancement in biological imaging. Utilizing the IRIS beamline at the BESSY II synchrotron source, the technique involves an ultra-thin silicon carbide membrane to enhance imaging capabilities, allowing for detailed analysis of cellular components, which can transform research in cancer and disease processes.
1. Nano-IR spectroscopy technique developed for imaging living cells.2. Overcomes limitations of imaging hydrated systems.3. Uses an ultra-thin silicon carbide membrane for imaging.4. Enabled by the IRIS beamline at BESSY II synchrotron.5. Allows detailed analysis of proteins, nucleic acids, and membrane lipids.6. Spatial resolution achieved below 10 nm.7. Potential applications in studying cancer and disease processes under native conditions.
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