Forty-Minute Point-of-Care Lung Cancer Test
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By
February 12, 2025
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2 min
UK scientists have developed a biosensor capable of rapidly and sensitively detecting lung cancer biomarkers in blood serum. The study describes a microfluidic-enabled electrochemical immunosensor designed to quantify carcinogenic embryonic antigen (CEA) and neuron-specific enolase (NSE), two well-established serum biomarkers for lung cancer. The biosensor has the potential to become a powerful point-of-care screening device, leading to early diagnosis of lung cancer and enabling prompt therapeutic interventions with improved clinical outcomes. Future developments could expand the system to detect additional biomarkers and refine its integration into clinical workflows.
1. UK scientists developed a biosensor to detect lung cancer biomarkers in blood serum. 2. The biosensor quantifies CEA and NSE. 3. It has the potential to enable early diagnosis and improved clinical outcomes. 4. The limits of detection for CEA and NSE in serum are 0.76 ng/mL and 0.52 ng/mL, respectively. 5. The biosensor shows linear responses in clinically relevant concentration ranges. 6. Future developments could expand the system to detect additional biomarkers and refine its integration into clinical workflows.
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