From the Journals

Sickle Cell Stroke Rates Rise Post-STOP

Despite STOP trial interventions, ischemic stroke rates for children in California with sickle cell disease increased by 42% from 1999-2009 to 2010-2019, a large population-based study reveals.

Share

A study published in Blood analyzed data from 7,636 Californians with sickle cell disease over a 28-year period and found a significant increase in ischemic stroke rates in both children and adults. The study revealed key risk factors such as hypertension, hyperlipidemia, and prior cerebrovascular disorders, contributing to the elevated stroke incidence. The research utilized the Health Care Access and Innovation database and demonstrated a trend of rising stroke rates in all age groups since the STOP trial in 1998. Findings also highlighted the high prevalence of comorbidities such as acute chest syndrome and renal failure among affected individuals.

Original Source(s)

Sickle Cell Stroke Rates Rise Post-STOP

Despite STOP trial interventions, ischemic stroke rates for children in California with sickle cell disease increased by 42% from 1999-2009 to 2010-2019, a large population-based study reveals.

  • by Kerri Miller

  • September 23, 2024

  • 5 min

Related Content

Diabetes, Amyloid-β Interaction Doubles MCI Risk

Managing diabetes may reduce Alzheimer’s risk, as 20-year data reveal synergistic brain changes from diabetes and amyloid-β abnormality.

Meds that May Increase Dementia Risk

Antimicrobials, anti-inflammatories, and vaccines were associated with reduced dementia risk, while antipsychotics, antidepressants, and diabetes medications were frequently associated with increased dementia risk.

Audiometric Hearing Loss Major Dementia Risk

"Up to 32% of incident dementia cases could be attributable to clinically significant audiometric hearing loss," revealing the potential impact of treating hearing impairment for dementia prevention in older adults.