From the Journals

Can Peptides Improve Skin Aging?

Systematic review reports gains in hydration, brightness, and wrinkles, with stronger evidence for oral vs topical formulations

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A systematic review and meta-analysis published in Frontiers in Medicine evaluated 19 randomized controlled trials, involving 1,341 patients, revealing that peptide-based therapies can improve signs of skin aging such as hydration, brightness, and wrinkle appearance. The analysis showed stronger evidence for oral peptide formulations over topical ones. Although the therapies were generally well tolerated with minimal adverse effects, the overall benefits were modest and varied across studies. The review calls for more standardized research to confirm the effectiveness and safety of these treatments.

Original Source(s)

Can Peptides Improve Skin Aging?

  • by Conexiant News Staff

  • March 18, 2026

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