From the Journals

Osteoporosis Linked to Increased Dry AMD Risk

Genetic and pooled observational data suggest a unidirectional association, with elevated odds of dry age-related macular degeneration and a stronger signal in women.

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Recent research in Experimental Gerontology indicates a significant association between osteoporosis and increased risk of age-related macular degeneration (AMD) in women. The meta-analysis of 58,057 patients revealed that women with osteoporosis had 1.5 times the odds of developing overall AMD. Sub-analyses showed a 1.6 times higher risk of early AMD, while the connection with advanced AMD was not significant. In contrast, this relationship did not hold for men. Using Mendelian randomization, the study suggested a unidirectional causal link from osteoporosis to dry AMD, implying a need for heightened awareness among clinicians regarding elderly women with osteoporosis.

Original Source(s)

Osteoporosis Linked to Increased Dry AMD Risk

Genetic and pooled observational data suggest a unidirectional association, with elevated odds of dry age-related macular degeneration and a stronger signal in women.

  • by Julie Greenbaum

  • February 24, 2026

  • 3 min

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