From the Journals

What Shapes Pediatric Platelet Response?

REDS-IV-P data examine how storage time, pathogen reduction, and donor factors affect transfusion outcomes in pediatric patients

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A multicenter cohort study published in JAMA Network Open analyzed 249,340 inpatient encounters involving platelet transfusions in neonates and children from April 2019 to June 2023. The study found significant variations in transfusion practices, with a median age of 2.5 years among transfused patients. The highest transfusion rates were observed in children aged 1 to 6 years. The study examined factors affecting posttransfusion outcomes, revealing that platelet additive solutions and donor demographics influenced transfusion efficacy and burden.

Original Source(s)

What Shapes Pediatric Platelet Response?

REDS-IV-P data examine how storage time, pathogen reduction, and donor factors affect transfusion outcomes in pediatric patients

  • by Jess Allerton

  • February 26, 2026

  • 3 min

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