HDL Cholesterol's Vitamin D Dance: A Gender Twist
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By
October 2, 2024
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3 min
A recent cross-sectional study explored the relationship between high-density lipoprotein cholesterol (HDL-C) and serum 25-hydroxyvitamin D [25(OH)D] in adults aged 20–59 years, revealing a significant positive association. Females showed a consistent positive association between HDL-C and 25(OH)D, while males exhibited an inverted U-shaped relationship. The study recommended simultaneous monitoring of HDL-C and vitamin D levels to enhance cardiovascular risk assessment, especially in males with lower HDL-C levels, and suggested increasing vitamin D intake for potential impact on cardiovascular and skeletal health outcomes.
1. Higher HDL cholesterol levels were associated with vitamin D in a recent study. 2. Females showed a consistent positive association between HDL-C and 25(OH)D, while males exhibited an inverted U-shaped relationship. 3. The study recommended simultaneous monitoring of HDL-C and vitamin D levels to enhance cardiovascular risk assessment, especially in males with lower HDL-C levels. 4. It suggested increasing vitamin D intake for potential impact on cardiovascular and skeletal health outcomes, particularly for men with lower HDL-C levels. 5. The study had limitations, including its cross-sectional design and potential unadjusted confounding factors.
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