From the Journals

Blood Tau Trajectories Tied to Alzheimer Onset

Repeated blood tau measurements were associated with age at symptom onset among individuals at risk for Alzheimer disease 

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Longitudinal measurements of the blood-based tau biomarker (p-tau217) have shown a correlation with the timing of symptom onset in cognitively unimpaired individuals at risk for Alzheimer’s disease, according to a study published in Nature Medicine. Researchers utilized data from the Knight Alzheimer Disease Research Center and the Alzheimer’s Disease Neuroimaging Initiative to develop individualized ‘biomarker clock’ models. These models can estimate age at biomarker positivity, aiding in clinical trial design, although prediction errors preclude clinical decision-making for individuals at this stage.

Original Source(s)

Blood Tau Trajectories Tied to Alzheimer Onset

Repeated blood tau measurements were associated with age at symptom onset among individuals at risk for Alzheimer disease 

  • by Henry Thomas

  • February 26, 2026

  • 3 min

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