Manual IVF Screening May Miss Additional Oocytes
Clinical study suggests automated system can recover mature oocytes overlooked during standard screening
A multicenter clinical study published in Nature Medicine reveals that the manual screening of follicular fluid during in vitro fertilization (IVF) may overlook additional oocytes, including those capable of fertilization. Researchers employed an automated microfluidic device (FIND-Chip) that successfully recovered extra oocytes from previously screened samples, resulting in viable embryos and even a live birth. The system, which isolates oocytes based on size rather than visual inspection, significantly enhanced the number of usable oocytes, raising important efficiency and outcome questions in IVF procedures.
1. Manual screening may miss additional mature oocytes. 2. FIND-Chip automated device recovers extra oocytes. 3. Over 40% of recovered oocytes were mature. 4. One patient achieved a live birth from a recovered oocyte. 5. System improves IVF workflow efficiency. 6. Raises questions about standard practices in IVF. 7. Potential to enhance live birth rates with more viable oocytes.