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Commentary & Perspectives

The New Path to ADCs

  • March 24, 2026

  • 11 min

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The World ADC London panel, featuring experts like Mohit Trikha and Bob Lutz, discussed the evolution of Antibody-Drug Conjugates (ADCs) focusing on enhancing patient tolerability and quality of life. The conversation emphasized that rather than solely improving potency, the industry must prioritize the management of adverse effects due to ADC treatments. Innovative payload designs, effective linkers, and patient-centered approaches could revolutionize ADC therapies by using selectivity to better target cancers while minimizing associated toxicities, ultimately allowing patients to live more comfortably.

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