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Could AI Unlock Mass Spectrometry’s Full Discovery Potential?

  • November 11, 2025

  • 9 min

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Matterwork's Large Spectral Model (LSM) represents a breakthrough in molecular discovery by utilizing self-supervised machine intelligence to analyze multi-omics data from mass spectrometry, drastically reducing the time needed for data interpretation. Niall O'Connor, CTO of Matterworks, highlights its capabilities in transforming LC-MS analysis by distinguishing chemical signals from noise and enhancing compound identification. The integration with Pyxis and Amy streamlines workflows, allowing researchers to derive actionable biological insights more efficiently than traditional methods, ultimately leading to improved accuracy in diagnostics and research.

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