Omadacycline for Pediatric CAP
Case details intravenous-to-oral strategy after multiple antibiotic hypersensitivity reactions
A 4-year-old girl with community-acquired pneumonia and multiple antibiotic hypersensitivities successfully improved after a 7-day intravenous treatment with omadacycline followed by oral doxycycline, showing no hypersensitivity reactions during the therapy. Initial symptoms included high fever and productive cough, with cultures identifying resistant Streptococcus pneumoniae and Mycoplasma pneumoniae. Clinicians opted for omadacycline due to mixed infections and antibiotic allergies, with follow-up demonstrating significant regression of lung consolidation. Future studies are needed to investigate omadacycline's safety and efficacy in pediatric cases.
1. 4-year-old girl with pneumonia and antibiotic hypersensitivities treated with omadacycline. 2. Symptoms included fever and productive cough. 3. Initial culture identified resistant Streptococcus pneumoniae and Mycoplasma pneumoniae. 4. Treatment included 7 days of intravenous omadacycline followed by oral doxycycline. 5. No hypersensitivity reactions during omadacycline therapy. 6. Follow-up showed regression of lung consolidation. 7. Call for prospective studies to evaluate omadacycline's efficacy in pediatrics.
