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ctDNA Test Guides Breast Care in Elderly

Blood-based monitoring may help tailor less invasive treatment decisions

  • March 31, 2026

  • 2 min

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A prospective study published in Clinical Cancer Research reveals that circulating tumor DNA (ctDNA) testing can help older women with estrogen receptor-positive breast cancer avoid surgery by assessing their eligibility for endocrine therapy. The research analyzed 43 patients aged 70 and older, finding that ctDNA status correlated with imaging results. It demonstrated that persistent ctDNA after six months indicated tumor progression, while negative ctDNA predicted stability. These findings propose ctDNA as a minimally invasive biomarker for real-time treatment monitoring and personalization in breast cancer management.

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ctDNA Test Guides Breast Care in Elderly

  • March 31, 2026

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