From the Journals

Tranexamic Acid in General Surgery: POISE-3 Findings

“Tranexamic acid significantly reduced the risk of perioperative bleeding without increasing cardiovascular risk in patients undergoing general surgery procedures,” said Lily J. Park, MD, MSc, and colleagues.

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A recent study evaluated the safety and efficacy of tranexamic acid (TXA) in reducing perioperative bleeding in general surgery patients. The study found that TXA significantly reduced the risk of major perioperative bleeding by 26% without increasing cardiovascular risks. Subgroup analyses also revealed significant reductions in bleeding risk among patients undergoing specific types of surgeries. Additionally, TXA was associated with a reduced need for transfusion of packed red blood cells without increasing thromboembolic events.

Original Source(s)

Tranexamic Acid in General Surgery: POISE-3 Findings

“Tranexamic acid significantly reduced the risk of perioperative bleeding without increasing cardiovascular risk in patients undergoing general surgery procedures,” said Lily J. Park, MD, MSc, and colleagues.

  • by Kathryn Wighton

  • January 23, 2025

  • 3 min

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