Oxidative Balance, Inflammation Linked to RA Mortality - Summary - MDSpire
From the Journals

Oxidative Balance, Inflammation Linked to RA Mortality

Higher oxidative balance was associated with lower mortality, while greater systemic inflammation was linked to increased risk in a US cohort of patients with rheumatoid arthritis.

Share

A retrospective cohort study published in Medicine highlights the relationship between oxidative balance, systemic inflammation, and all-cause mortality in patients with rheumatoid arthritis. Analyzing data from 24,552 adults, it reveals that a 1-point increase in oxidative balance corresponds to a 4% reduction in mortality risk, while higher systemic inflammation is linked to a 14% increase. Specifically, patients with low oxidative balance and high inflammation exhibited the poorest survival rates. Various thresholds for risk stratification are proposed, albeit with noted limitations in the study design.

Original Source(s)

Oxidative Balance, Inflammation Linked to RA Mortality

  • by Andrea Surnit

  • April 20, 2026

Related Content

PR Flares Linked to Future Arthritis Sites

Persistent arthritis often develops in joints affected during earlier flares

Organ Damage, BMI Linked to Fatigue in SLE

Cross-sectional study suggests fatigue is associated with damage accrual and body mass, not disease activity

Reproductive Health Framework for Care

Narrative review and commentary proposes framework to address care gaps beyond disease control