From the Journals

Rethinking Prehabilitation Before Surgery

Researchers compare personalized versus standard prehabilitation and examine functional, immune, and postoperative outcomes before major elective surgery.

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Researchers conducted a randomized clinical trial published in JAMA Surgery, examining immune profiling to explore the differences between personalized and standard prehabilitation approaches before surgery. Findings indicated that personalized interventions linked with remote coaching yielded significant preoperative immune signaling differences and improved functional and cognitive outcomes. Patients receiving personalized prehabilitation showed fewer severe postoperative complications, emphasizing the potential for tailored interventions to enhance surgical readiness. The study calls for larger trials to validate these findings.

Original Source(s)

Rethinking Prehabilitation Before Surgery

Researchers compare personalized versus standard prehabilitation and examine functional, immune, and postoperative outcomes before major elective surgery.

  • by Kathryn Wighton

  • February 2, 2026

  • 4 min

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