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Dynamic, Accessible Risk Stratification Tool Created for Smoldering Multiple Myeloma

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Researchers have developed a dynamic risk stratification tool for patients with smoldering multiple myeloma called PANGEA-SMM, which effectively predicts progression to active disease. This online tool integrates evolving biomarker data and outperforms existing models like 20/2/20 and IMWG in accuracy. The cohort study included 2,344 patients across international centers. By monitoring changes in specific biomarkers, the tool helps identify high-risk patients who may require early intervention, enhancing patient management strategies.

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