MDSpire - Summary
From the Journals

Progesterone Linked to Brain Structure Changes

MRI study finds stronger associations than estradiol across menstrual phases

Share

A recent study published in eBioMedicine examined how fluctuations in sex hormones across the menstrual cycle impact brain structure in 32 healthy women. The research found that progesterone exhibits stronger associations with brain morphology compared to estradiol. Comparing periods of low hormone levels during menstruation and the periovulatory phase, researchers observed a statistically significant increase in total gray matter volume linked to higher progesterone levels. These findings underscore progesterone's potential role in neuroplasticity and brain development, while noting limitations in generalizability due to sample size.

Original Source(s)

Progesterone Linked to Brain Structure Changes

  • by Meg Barbor

  • March 30, 2026

Related Content

Reducing Constipation in Parkinson’s, Step by Step

A 3-month walking program was associated with improved constipation symptoms and lower Parkinson’s disease severity scores in a small uncontrolled pre–post study

FDA Updates SMA Treatment Dosing

A higher-dose nusinersen regimen for spinal muscular atrophy demonstrated statistically significant motor function improvement in treatment-naïve infants in the DEVOTE trial with a safety profile consistent with prior dosing.

Zack Z. Ramilevich, M.D., Joins Marcus Neuroscience Institute as a General Neurologist

Board-certified neurologist Zack Z. Ramilevich, M.D., has joined Marcus Neuroscience Institute, part of Baptist Health, as a general neurologist.

  • by

  • March 26, 2026

  • 2 min