HS Linked to Higher Cancer Risk - Summary - MDSpire
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HS Linked to Higher Cancer Risk

Investigators report site-specific cancer associations and limited adjusted estimates in meta-analysis.

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A systematic review and meta-analysis have revealed that patients with hidradenitis suppurativa (HS) have 1.82 times greater odds of developing cancer compared to the general population. Eleven studies, involving over 624,000 HS patients, indicated increased cancer risks, particularly in head and neck, respiratory, hematologic, and gastrointestinal cancers. While lymphoma subtypes showed varied associations, the overall cancer risk for HS patients remains low. Factors like inflammation and comorbid conditions may contribute to these associations, though reporting limitations exist, particularly concerning lifestyle influences like smoking and obesity.

Original Source(s)

HS Linked to Higher Cancer Risk

  • by Kathryn Wighton

  • April 6, 2026

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