Alzheimer Biomarkers Higher in Women
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By
January 30, 2026
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3 min
A recent study led by Dr. Merve Akinci from Columbia University reveals that women in their 60s exhibit greater Alzheimer pathology compared to men, despite showing signs of structural brain resilience. This cross-sectional study involved 503 participants, highlighting a stronger amyloid and tau burden in women, particularly influenced by the presence of apolipoprotein E epsilon 4. While women demonstrated a higher cortical thickness in regions early affected by Alzheimer, factors such as vascular health were found to potentially influence these results, calling for larger studies to explore these dynamics further.
1. Study led by Dr. Merve Akinci, involving 503 participants aged 60-69.2. Women showed greater amyloid and tau burden than men.3. Apolipoprotein E epsilon 4 status significantly affected tau burden differences.4. Women had greater cortical thickness in areas impacted by Alzheimer's disease.5. Vascular health factors influenced amyloid and tau pathology results.6. Study highlights need for larger, balanced cohorts in future research.
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