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National Institutes of Health Builds Digital Model of RPE Cells

AI-driven 3D model maps polarity changes relevant to AMD progression

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  • February 27, 2026

  • 2 min

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A team from the National Institutes of Health has pioneered a three-dimensional 'digital twin' model of retinal pigment epithelium (RPE) cells, providing valuable insights into age-related macular degeneration (AMD). Utilizing induced pluripotent stem cell-derived RPE and sophisticated AI algorithms, they analyzed cellular organization and structural changes. This model serves as a reference to identify disruptions in polarity associated with AMD, potentially paving the way for therapeutic developments for various diseases affecting cellular organization.

Original Source(s)

National Institutes of Health Builds Digital Model of RPE Cells

AI-driven 3D model maps polarity changes relevant to AMD progression

  • February 27, 2026

  • 2 min

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