From the Journals

Hydrogel-Based Biosensor Enables Real-Time Detection of Oral Inflammation

Study describes adhesive intraoral device that measures TNF-alpha levels chairside, potentially supporting earlier diagnosis of periodontal and pulp disease.

Share

Researchers from Michigan State University have developed a new biosensor, known as the tissue-adhesive hydrogel–MXene (TAHM), designed to detect oral inflammation in real-time during dental check-ups. This device measures tumor necrosis factor (TNF)-alpha, a key marker for inflammation linked to conditions like pulpitis and periodontitis. Early detection via this biosensor could prevent serious complications, including tooth loss, providing a significant advancement over traditional diagnostic methods that often rely on subjective assessments. The biosensor has shown promising results in laboratory tests and preclinical models, demonstrating its potential for point-of-care applications in dentistry.

Original Source(s)

Hydrogel-Based Biosensor Enables Real-Time Detection of Oral Inflammation

Study describes adhesive intraoral device that measures TNF-alpha levels chairside, potentially supporting earlier diagnosis of periodontal and pulp disease.

  • by Olivia Anderson

  • February 25, 2026

  • 3 min

Related Content

The Smile Seminar To Benefit Operation Smile

The Smile Seminar To Benefit Operation Smi...

Digital Photography Enhances Diagnostics, Communication, and Documentation

Reviews the applications and various types of available dental photography equipment.

Bulk EZ PLUS™: Dual-Cure Bulk-Fill Composite Ideal for Direct Restorations