From the Journals

Potential New Lyme Disease Therapy Advances to Human Safety Trials

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The novel antibiotic therapy, hygromycin A, has advanced to human safety trials as a potential future treatment for Lyme disease. It is designed to target spirochetes bacteria, including Borrelia burgdorferi, and may eliminate residual pathogens that lead to chronic Lyme disease. Positive safety findings in preclinical models have led to upcoming human trials in Australia, expected to conclude in the fall of 2024, with hopes for positive results. - Kim Lewis, PhD, Distinguished Professor of Biology at the Northeastern University College of Science

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