From the Journals

Side Effects: When the Obvious Call Is the Wrong One

Dialysis, nicotine, caffeine, and tattoos — four studies that quietly rearrange what good clinical instinct looks like.

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Recent findings challenge the long-held belief that early initiation of dialysis improves outcomes in critically ill patients with acute kidney injury. Studies indicate that early dialysis does not benefit mortality rates and may lead to increased catheter infections and fluid imbalances. Meanwhile, a study suggests that paternal nicotine exposure may enhance glucose metabolism in offspring, indicating epigenetic influences before conception. Moreover, a Canadian study highlights the detrimental impact of pre-workout supplements on adolescent sleep patterns, suggesting a need for awareness in young athletic populations.

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Side Effects: When the Obvious Call Is the Wrong One

  • by Kerri Miller

  • March 17, 2026

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