COVID-19 Booster in Pregnancy Linked to Higher Infant Antibodies
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August 15, 2025
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2 min
A U.S. cohort study involving 518 infants found that those whose mothers received a COVID-19 booster during pregnancy showed significantly higher antibody levels at birth, 2 months, and 6 months compared to infants of mothers who had only two vaccine doses or were vaccinated postpartum. Conducted from July 6, 2021, to January 31, 2022, at nine academic centers, the research revealed that transplacental transfer of antibodies was more effective with a booster dose, suggesting enhanced immunity in infants. No hospitalizations or deaths occurred among the participants.
1. Study involved 518 infants and focused on maternal COVID-19 vaccination effects. 2. Grouped by booster dose, two doses, or postpartum vaccination. 3. Enhanced antibody levels were noted in infants of mothers with a booster. 4. Transplacental transfer was more efficient in the booster group. 5. No hospitalizations or deaths in the infant cohort. 6. Maternal COVID-19 infection linked to higher antibody levels. 7. Breastfeeding did not influence antibody levels.
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