The application of the revised obesity definition by the Lancet Commission reveals a significant increase in obesity prevalence among U.S. adults, rising from 43% to 69% due to the inclusion of anthropometric-only obesity. This study analyzed 301,026 participants from the All of Us Research Program, showcasing that 36% met criteria for clinical obesity, which escalated with age. The findings reveal different obesity phenotypes and underline the heightened risks for organ dysfunction and several chronic conditions linked to obesity, particularly in older adults. Published in JAMA Network Open, the research emphasizes the need for updated criteria in obesity assessment and clinical management.
1. 69% of U.S. adults meet the revised obesity criteria, up from 43%.2. Median age of participants was 54; 61% were female.3. 36% met criteria for clinical obesity.4. Obesity increases with age, notably affecting 54% of those aged 70 and older.5. Two obesity phenotypes identified: BMI-plus-anthropometric and anthropometric-only.6. Increased organ dysfunction risks associated with BMI-plus-anthropometric obesity.7. Racial disparities noted in obesity prevalence and treatment eligibility.8. Study funded by multiple NIH grants.
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