Lupus Disease Activity Linked to Incontinence
January 8, 2026
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3 min
A recent study found that over one-third of adults with systemic lupus erythematosus (SLE) experience urinary incontinence (UI), with 17% of young adults aged 18 to 34 affected. In a cohort of 425 adults, higher disease activity correlated with a nearly threefold increase in UI risk. The most common subtype was mixed-type UI, significantly impacting daily functioning. Conducted within the Approaches to Positive, Patient-Centered Experiences of Aging in Lupus study, this cross-sectional analysis highlights the need to address UI in SLE management, especially for those with active disease or neuropsychiatric symptoms.
1. Over one-third of adults with SLE report urinary incontinence.2. Higher disease activity is linked to increased odds of UI.3. Mixed-type UI is the most common form reported.4. Many patients report clinically significant impacts on daily function.5. The study highlights underreporting of UI in clinical settings.6. Neuropsychiatric damage shows a strong association with UI.7. The study was conducted from October 2019 to May 2022.
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